Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Epigenetic Regulation01:37

Epigenetic Regulation

3.2K
Epigenetic changes alter the physical structure of the DNA without changing the genetic sequence and often regulate whether genes are turned on or off. This regulation ensures that each cell produces only proteins necessary for its function. For example, proteins that promote bone growth are not produced in muscle cells. Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
X-chromosome...
3.2K
Genomic Imprinting and Inheritance02:30

Genomic Imprinting and Inheritance

35.5K
Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
35.5K
Epistasis01:39

Epistasis

48.0K
In addition to multiple alleles at the same locus influencing traits, numerous genes or alleles at different locations may interact and influence phenotypes in a phenomenon called epistasis. For example, rabbit fur can be black or brown depending on whether the animal is homozygous dominant or heterozygous at a TYRP1 locus. However, if the rabbit is also homozygous recessive at a locus on the tyrosinase gene (TYR), it will have an unshaded coat that appears white, regardless of its TYRP1...
48.0K
Epistasis Analysis01:09

Epistasis Analysis

5.3K
Although Mendel chose seven unrelated traits in peas to study gene segregation, most traits involve multiple gene interactions that create a spectrum of phenotypes. When the interaction of various genes or alleles at different locations influences a phenotype, this is called epistasis. Epistasis often involves one gene masking or interfering with the expression of another (antagonistic epistasis). Epistasis often occurs when different genes are part of the same biochemical pathway. The...
5.3K
The Central Dogma01:20

The Central Dogma

28.8K
The central dogma explains the flow of genetic information from DNA nucleotides to the amino acid sequence of proteins.
RNA is the Missing Link Between DNA and Proteins
In the early 1900s, scientists discovered that DNA stores all the information needed for cellular functions and that proteins perform most of these functions. However, the mechanisms of converting genetic information into functional proteins remained unknown for many years. Initially, it was believed that a single gene is...
28.8K
Chromatin Modification in iPS Cells01:32

Chromatin Modification in iPS Cells

2.0K
Chromatin modification alters gene expression; therefore, scientists can add histone-modifying enzymes, histone variants, and chromatin remodeling complexes to somatic cells to aid reprogramming into pluripotent stem (iPS) cells.
Compact chromatin makes reprogramming difficult. Enzymes, such as histone demethylases and acetyltransferases, are often added during reprogramming to loosen the chromatin, making the DNA more accessible to transcription factors. Molecules that inhibit histone...
2.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

To Farm or Not to Farm? Pilot Testing a Sentiocentric Ethical Framework for Farming Non-Typical Species.

Animals : an open access journal from MDPI·2026
Same author

PLLA/GO Scaffolds Filled with Canine Placenta Hydrogel and Mesenchymal Stem Cells for Bone Repair in Goat Mandibles.

Journal of functional biomaterials·2024
Same author

Lameness in Pregnant Sows Alters Placental Stress Response.

Animals : an open access journal from MDPI·2023
Same author

Changes in Stereotypies: Effects over Time and over Generations.

Animals : an open access journal from MDPI·2022
Same author

Housing Conditions and a Challenge with Lipopolysaccharide on the Day of Estrus Can Influence Gene Expression of the Corpus Luteum in Gilts.

Genes·2022
Same author

Initial steps on mapping differentially expressed proteins in bovine preantral follicles and ovarian tissue: An approach using single-follicle MALDI-MS and mass spectrometry imaging (MSI) analysis.

Reproduction in domestic animals = Zuchthygiene·2021

Related Experiment Video

Updated: Oct 7, 2025

Providing Meaningful Environmental Enrichment and Measuring Saliva Cortisol in Pigs Housed on Slatted Flooring
07:02

Providing Meaningful Environmental Enrichment and Measuring Saliva Cortisol in Pigs Housed on Slatted Flooring

Published on: September 30, 2019

7.3K

How Epigenetics Can Enhance Pig Welfare?

Arthur Nery da Silva1, Michelle Silva Araujo1, Fábio Pértille2

  • 1Department of Preventive Veterinary Medicine and Animal Health, School of Veterinary Medicine and Animal Science, Campus "Fernando Costa", University of São Paulo, Pirassununga 13635-900, Brazil.

Animals : an Open Access Journal From MDPI
|January 11, 2022
PubMed
Summary

Epigenetic biomarkers can reveal stress in farm animals, improving welfare. This review identifies potential stress markers in swine to enhance animal welfare certification and consumer trust.

Keywords:
DNA methylationbiomarkersepigeneticsstressswinewelfare certification

More Related Videos

Transition of Farm Pigs to Research Pigs using a Designated Checklist followed by Initiation of Clicker Training - a Refinement Initiative
07:59

Transition of Farm Pigs to Research Pigs using a Designated Checklist followed by Initiation of Clicker Training - a Refinement Initiative

Published on: August 21, 2021

5.6K
Isolation, Culture, and Genetic Engineering of Mammalian Primary Pigment Epithelial Cells for Non-Viral Gene Therapy
09:46

Isolation, Culture, and Genetic Engineering of Mammalian Primary Pigment Epithelial Cells for Non-Viral Gene Therapy

Published on: February 26, 2021

3.3K

Related Experiment Videos

Last Updated: Oct 7, 2025

Providing Meaningful Environmental Enrichment and Measuring Saliva Cortisol in Pigs Housed on Slatted Flooring
07:02

Providing Meaningful Environmental Enrichment and Measuring Saliva Cortisol in Pigs Housed on Slatted Flooring

Published on: September 30, 2019

7.3K
Transition of Farm Pigs to Research Pigs using a Designated Checklist followed by Initiation of Clicker Training - a Refinement Initiative
07:59

Transition of Farm Pigs to Research Pigs using a Designated Checklist followed by Initiation of Clicker Training - a Refinement Initiative

Published on: August 21, 2021

5.6K
Isolation, Culture, and Genetic Engineering of Mammalian Primary Pigment Epithelial Cells for Non-Viral Gene Therapy
09:46

Isolation, Culture, and Genetic Engineering of Mammalian Primary Pigment Epithelial Cells for Non-Viral Gene Therapy

Published on: February 26, 2021

3.3K

Area of Science:

  • Epigenetics and its role in environmental adaptation.
  • Application of epigenetics in animal welfare.

Background:

  • Epigenetics mediates phenotypic plasticity, influencing individual adaptation.
  • Growing evidence supports epigenetic biomarkers for stress detection in farm animals.

Purpose of the Study:

  • Evaluate existing stress epi-biomarkers in swine.
  • Encourage development of molecular tools for animal welfare certification.

Main Methods:

  • Literature review of swine production, farm management, and welfare implications.
  • Analysis of stress-related genes and differentially methylated regions (DMRs) in swine under various stress conditions.
  • Functional enrichment analysis of DMRs.

Main Results:

  • Identified potential stress-related genes and DMRs in swine.
  • Highlighted implications of farm management on animal welfare and epigenome.
  • Identified potential epi-biomarkers for targeted analysis.

Conclusions:

  • Potential epi-biomarkers can be integrated into animal welfare certification schemes.
  • Molecular tools based on epigenetics can enhance animal welfare certification.
  • This technology may increase consumer confidence in animal welfare standards.