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Updated: Oct 7, 2025

Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction
Published on: May 28, 2019
Conditioning Program Prescribed from the External Training Load Corresponding to the Lactate Threshold Improved
Alejandro Zamora Restan1, Aparecido Antonio Camacho2, Evandro Zacché2
1Department of Animal Morphology and Physiology, Laboratory of Pharmacology and Equine Exercise Physiology (LAFEQ), School of Agricultural and Veterinarian Sciences (FCAV), São Paulo State University (UNESP), Jaboticabal 14884-900, São Paulo, Brazil.
Endurance training improved canine heart function. Athletic training enhanced systolic and diastolic functions, as measured by echocardiography, promoting better heart health and potentially preventing injuries.
Area of Science:
- Veterinary Cardiology
- Canine Sports Medicine
- Cardiovascular Physiology
Background:
- Systolic and diastolic function changes in athletic dogs are not fully understood.
- Endurance training programs (ETP) can impact cardiac function.
- Lactate threshold (VLT) velocity is a key metric for prescribing training intensity.
Purpose of the Study:
- To investigate the effects of an endurance training program on systolic and diastolic cardiac functions in Beagle dogs.
- To evaluate echocardiographic changes associated with ETP.
- To determine if training prescribed by lactate threshold velocity improves myocardial function.
Main Methods:
- Eighteen Beagle dogs were divided into control and trained groups.
- The trained group underwent an 8-week ETP at 70-80% of VLT velocity.
- Echocardiography (2D, M-mode, Doppler, 2D speckle tracking) and Principal Component Analysis (PCA) were used for evaluation before and after training.
Main Results:
- ETP significantly improved left ventricular internal dimension at end diastole (LVDd) and the LVDd:Ao ratio.
- Strain rate indices, reflecting myocardial function, were also enhanced.
- PCA effectively captured echocardiographic alterations induced by ETP.
Conclusions:
- Lactate threshold-based endurance training positively impacts both diastolic and systolic cardiac functions in dogs.
- These improvements suggest potential benefits for myocardial health and injury mitigation.
- Echocardiography and PCA are valuable tools for assessing training-induced cardiac adaptations.
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