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Published on: February 8, 2017
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Nanostructured Lipid Carriers-Hydrogels System for Drug Delivery: Nanohybrid Technology Perspective
Sharifah Nurfadhlin Afifah Syed Azhar1,2, Siti Efliza Ashari1,3, Norhazlin Zainuddin2
1Integrated Chemical BioPhysics Research Centre (iCheBP), Faculty of Science, Universiti Putra Malaysia (UPM), Serdang 43400, Selangor, Malaysia.
Molecules (Basel, Switzerland)
|January 11, 2022
Summary
Advanced nanohybrid systems combine nanostructured lipid carriers (NLC) and hydrogels for enhanced drug delivery. This review explores their preparation, applications, and benefits, highlighting improved mechanical strength and reduced NLC aggregation.
Area of Science:
- Nanotechnology
- Materials Science
- Pharmaceutical Sciences
Background:
- Nanotechnology enables advanced hybrid components for superior drug delivery.
- Nanostructured lipid carriers (NLC) and hydrogel systems are key components in drug delivery.
- Hybrid systems offer synergistic properties not achievable by individual components.
Purpose of the Study:
- To review nanohybrid perspectives in drug delivery, focusing on NLC and hydrogel systems.
- To highlight the synergistic benefits of combining NLC with hydrogels.
- To provide an overview of preparation methods, applications, advantages, and challenges of NLC-hydrogel hybrids.
Main Methods:
- Literature review of scientific publications on NLC-hydrogel hybrid systems.
- Analysis of preparation techniques for nanostructured lipid carriers-hydrogel composites.
- Evaluation of reported applications and performance data.
Main Results:
- Hybrid NLC-hydrogel systems demonstrate enhanced mechanical strength of hydrogels.
- Aggregation of NLC is significantly reduced in hybrid systems.
- These hybrids show potential for improved drug loading and controlled release.
Conclusions:
- NLC-hydrogel hybrids represent a promising advancement in drug delivery technology.
- The synergistic combination offers enhanced material properties and drug delivery efficacy.
- Further research is needed to address challenges and fully realize the potential of these materials.
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