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Related Concept Videos

Thermosensation01:43

Thermosensation

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Peripheral thermosensation is the perception of external temperature. A change in temperature (on the surface of the skin and other tissues) is detected by a family of temperature-sensitive ion channels called Transient Receptor Potential, or TRP, receptors. These receptors are located on free nerve endings. Those detecting cold temperatures are closer to the surface of the skin than the nerve endings detecting warmth. These thermoTRP channels, while temperature selective, have relatively...
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Implicit personality theory explains how individuals make assumptions about the relationships between personality traits, behaviors, and character types. When people learn that someone possesses a particular trait, they tend to infer the presence of other related characteristics, forming a cohesive impression. This cognitive shortcut plays a crucial role in social interactions and interpersonal judgments.Central Traits and Their InfluenceSolomon Asch's seminal 1946 study highlighted the power...
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Heat and temperature are essential concepts for everyone every day. The study of heat and temperature is part of an area of physics known as thermodynamics. It is not always easy to distinguish heat and temperature.
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Every organism has an optimum temperature range within which healthy growth and physiological functioning can occur. At the ends of this range, there will be a minimum and maximum temperature that interrupt biological processes.
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The spontaneity of a process depends upon the temperature of the system. Phase transitions, for example, will proceed spontaneously in one direction or the other depending upon the temperature of the substance in question. Likewise, some chemical reactions can also exhibit temperature-dependent spontaneities. To illustrate this concept, the equation relating free energy change to the enthalpy and entropy changes for the process is considered:
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When a substance—isolated from its environment—is subjected to heat changes, corresponding changes in temperature and phase of the substance is observed; this is graphically represented by heating and cooling curves.
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Related Experiment Video

Updated: Oct 7, 2025

Field-Based Thermal Physiology Assay: Cold Shock Recovery under Ambient Conditions
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Hot and Cold Theory: Future Perspective.

Maryam Yavari1,2

  • 1Canadian College of Naturopathic Medicine, Toronto, ON, Canada. myavari@ccnm.edu.

Advances in Experimental Medicine and Biology
|January 11, 2022
PubMed
Summary
This summary is machine-generated.

The traditional "hot and cold" theory, ignored by conventional medicine, shows promise in personalized health maintenance and disease prevention. Modern research supports its holistic approach for future personalized medicine applications.

Keywords:
Holistic medicineHot–coldPersonalized medicinePrecision medicineTemperamentWhole system research

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Area of Science:

  • Integrative Medicine
  • Personalized Medicine
  • Systems Biology

Background:

  • Traditional and folk medicines worldwide utilize the "hot and cold" theory to explain individual differences along a hotness-coldness spectrum.
  • Conventional medicine has largely overlooked this holistic concept due to reductionist trends.
  • Recent research across various fields is beginning to validate the efficacy of this personalized approach.

Purpose of the Study:

  • To investigate the physiopathology and clinical effectiveness of the traditional "hot and cold" theory.
  • To explore how this concept can be integrated into modern healthcare.
  • To pave the way for future personalized medicine.

Main Methods:

  • Systems biology studies
  • Innovative modified clinical trials
  • Whole system research

Main Results:

  • Emerging studies support the efficacy of the "hot and cold" theory in health maintenance.
  • Evidence suggests its utility in disease prevention and treatment.
  • The holistic and personalized nature of this approach is being increasingly recognized.

Conclusions:

  • The "hot and cold" theory offers a valuable framework for personalized medicine.
  • Further research using systems biology and modified clinical trials is warranted.
  • This traditional concept holds potential for advancing contemporary healthcare practices.