Truly Multicolor Emissive Hyperbranched Polysiloxane: Synthesis, Mechanism Study, and Visualization of Controlled...

Unconventional fluorescent polymers have attracted increasing attention due to their facile synthesis, excellent biocompatibility, and novel photophysical properties. In this work, a truly multicolor emissive hyperbranched polysiloxane (HBPSi-β-CD) is obtained through adjusting the distribution of electron-rich atoms and grafting β-cyclodextrin; the quantum yields of HBPSi-β-CD after being excited by 360, 420, 450, and 550 nm are 19.36, 31.46, 46.14 and 44.84%, respectively. The density functional theory calculations reveal that the truly multicolor emission is derived from the formed electron delocalization among the hydroxyl, amine, ether, and -Si(O)₃ groups due to the strong intermolecular interaction, high density of electron-rich atoms, and low steric hindrance among functional groups. The prepared polymers could serve as a multisensitivity sensor in detecting Fe³⁺, Cu²⁺, and Co²⁺. The HBPSi-β-CD shows low cytotoxicity and excellent cellular imaging capability. The self-assembly of HBPSi-β-CD also possesses high drug loading capacity and pH-controlled drug release, especially, the drug delivery system could be applied in the visualization of controlled drug delivery.