A Multidisciplinary Approach to the First Autochthonous Case of Tularemia Reported in Portugal
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Detection of Abnormal Prion Protein by Immunohistochemistry
Published on: May 5, 2023
Flávia Cunha1, Isabel Lopes de Carvalho2, Carolina Torres3
1Serviço de Doenças Infeciosas. Centro Hospitalar e Universitário de Coimbra. Coimbra. Portugal.
Abstract:
Francisella tularensis, a Gram-negative coccobacillus, is a highly virulent pathogen responsible for several zoonotic outbreaks in Europe in the last few decades. The authors report the case of a 46-year-old male who developed fever, myalgias and headache a week after having contact with animal feed contaminated by rodents. Serological tests were positive for Francisella tularensis. This first case of autochthonous tularemia in Portugal led to an intensive investigation involving several healthcare services and national governmental authorities. The authors address the possible underdiagnosis of this infection in the country.

