Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving01:29

Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving

115
Mechanistic models play a crucial role in algorithms for numerical problem-solving, particularly in nonlinear mixed effects modeling (NMEM). These models aim to minimize specific objective functions by evaluating various parameter estimates, leading to the development of systematic algorithms. In some cases, linearization techniques approximate the model using linear equations.
In individual population analyses, different algorithms are employed, such as Cauchy's method, which uses a...
115
Residuals and Least-Squares Property01:11

Residuals and Least-Squares Property

8.0K
The vertical distance between the actual value of y and the estimated value of y. In other words, it measures the vertical distance between the actual data point and the predicted point on the line
If the observed data point lies above the line, the residual is positive, and the line underestimates the actual data value for y. If the observed data point lies below the line, the residual is negative, and the line overestimates the actual data value for y.
The process of fitting the best-fit...
8.0K
Calibration Curves: Linear Least Squares01:20

Calibration Curves: Linear Least Squares

3.0K
A calibration curve is a plot of the instrument's response against a series of known concentrations of a substance. This curve is used to set the instrument response levels, using the substance and its concentrations as standards. Alternatively, or additionally, an equation is fitted to the calibration curve plot and subsequently used to calculate the unknown concentrations of other samples reliably.
For data that follow a straight line, the standard method for fitting is the linear...
3.0K
Linear Approximation in Time Domain01:21

Linear Approximation in Time Domain

136
Nonlinear systems often require sophisticated approaches for accurate modeling and analysis, with state-space representation being particularly effective. This method is especially useful for systems where variables and parameters vary with time or operating conditions, such as in a simple pendulum or a translational mechanical system with nonlinear springs.
For a simple pendulum with a mass evenly distributed along its length and the center of mass located at half the pendulum's length,...
136
One-Compartment Open Model: Wagner-Nelson and Loo Riegelman Method for ka Estimation01:24

One-Compartment Open Model: Wagner-Nelson and Loo Riegelman Method for ka Estimation

783
This lesson introduces two critical methods in pharmacokinetics, the Wagner-Nelson and Loo-Riegelman methods, used for estimating the absorption rate constant (ka) for drugs administered via non-intravenous routes. The Wagner-Nelson method relates ka to the plasma concentration derived from the slope of a semilog percent unabsorbed time plot. However, it is limited to drugs with one-compartment kinetics and can be impacted by factors like gastrointestinal motility or enzymatic degradation.
On...
783
Linear Approximation in Frequency Domain01:26

Linear Approximation in Frequency Domain

164
Linear systems are characterized by two main properties: superposition and homogeneity. Superposition allows the response to multiple inputs to be the sum of the responses to each individual input. Homogeneity ensures that scaling an input by a scalar results in the response being scaled by the same scalar.
In contrast, nonlinear systems do not inherently possess these properties. However, for small deviations around an operating point, a nonlinear system can often be approximated as linear....
164

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Kernel Reboot: Breaking the Boundaries of Neural Tangent Kernels for Neural Fields.

IEEE transactions on pattern analysis and machine intelligence·2026
Same author

Description of a collaborative sperm whale birth and shifts in coda vocal styles during key events.

Scientific reports·2026
Same author

Cooperation by non-kin during birth underpins sperm whale social complexity.

Science (New York, N.Y.)·2026
Same author

Predicting mesoscale movement of sperm whale units in the Caribbean based on social dynamics.

Scientific reports·2025
Same author

Cancer Incidence and Mortality in Familial Adenomatous Polyposis Syndrome.

Diseases of the colon and rectum·2025
Same author

Surveillance Outcomes in Patients With a Family History of Colorectal Cancer in Both Parents.

Gastro hep advances·2024

Related Experiment Video

Updated: Oct 7, 2025

Design and Application of a Fault Detection Method Based on Adaptive Filters and Rotational Speed Estimation for an Electro-Hydrostatic Actuator
06:45

Design and Application of a Fault Detection Method Based on Adaptive Filters and Rotational Speed Estimation for an Electro-Hydrostatic Actuator

Published on: October 28, 2022

1.8K

Fast and Accurate Least-Mean-Squares Solvers for High Dimensional Data.

Alaa Maalouf, Ibrahim Jubran, Dan Feldman

    IEEE Transactions on Pattern Analysis and Machine Intelligence
    |January 11, 2022
    PubMed
    Summary
    This summary is machine-generated.

    We developed a faster algorithm for finding a subset of vectors for least-mean-squares (LMS) solvers, improving performance by up to 100x. This method efficiently summarizes large datasets for machine learning applications.

    More Related Videos

    ARL Spectral Fitting as an Application to Augment Spectral Data via Franck-Condon Lineshape Analysis and Color Analysis
    07:11

    ARL Spectral Fitting as an Application to Augment Spectral Data via Franck-Condon Lineshape Analysis and Color Analysis

    Published on: August 19, 2021

    2.6K
    ExCYT: A Graphical User Interface for Streamlining Analysis of High-Dimensional Cytometry Data
    05:12

    ExCYT: A Graphical User Interface for Streamlining Analysis of High-Dimensional Cytometry Data

    Published on: January 16, 2019

    11.6K

    Related Experiment Videos

    Last Updated: Oct 7, 2025

    Design and Application of a Fault Detection Method Based on Adaptive Filters and Rotational Speed Estimation for an Electro-Hydrostatic Actuator
    06:45

    Design and Application of a Fault Detection Method Based on Adaptive Filters and Rotational Speed Estimation for an Electro-Hydrostatic Actuator

    Published on: October 28, 2022

    1.8K
    ARL Spectral Fitting as an Application to Augment Spectral Data via Franck-Condon Lineshape Analysis and Color Analysis
    07:11

    ARL Spectral Fitting as an Application to Augment Spectral Data via Franck-Condon Lineshape Analysis and Color Analysis

    Published on: August 19, 2021

    2.6K
    ExCYT: A Graphical User Interface for Streamlining Analysis of High-Dimensional Cytometry Data
    05:12

    ExCYT: A Graphical User Interface for Streamlining Analysis of High-Dimensional Cytometry Data

    Published on: January 16, 2019

    11.6K

    Area of Science:

    • Machine Learning
    • Computational Geometry
    • Data Summarization

    Background:

    • Least-mean-squares (LMS) solvers are fundamental in machine learning and matrix factorization.
    • Existing methods for finding representative vector subsets are computationally expensive.
    • Caratheodory's Theorem provides a constructive proof but is impractical for large datasets.

    Purpose of the Study:

    • To develop an efficient algorithm for identifying a subset of d+1 vectors with positive weights whose weighted sum matches the original set.
    • To significantly improve the performance of existing LMS solvers.
    • To enable efficient data summarization for large-scale machine learning.

    Main Methods:

    • A novel algorithm with O(nd+d^4logn) time complexity, utilizing Caratheodory's construction on small, optimized subsets.
    • Fusion of data summarization techniques: sketches and coresets.
    • A faster O(nd) construction for high-dimensional data, yielding a weighted subset of O(d) sparsified points.

    Main Results:

    • The proposed algorithm significantly outperforms existing methods in speed.
    • Achieved performance boosts of up to 100x for LMS solvers in libraries like scikit-learn.
    • Demonstrated the effectiveness of combining sketches and coresets for data summarization.

    Conclusions:

    • The new algorithm offers a practical and efficient solution for vector subset selection in LMS problems.
    • The approach is generalizable to streaming and distributed data settings.
    • Provides a valuable tool for accelerating machine learning computations and enabling analysis of larger datasets.