Related Experiment Video
Updated: Oct 7, 2025

A Novel High-Throughput Ex Vivo Ovine Skin Wound Model for Testing Emerging Antibiotics
Published on: September 16, 2022
Antibacterial activity of cinnamon and clove oil against wound pathogens
P Anandhi1, M Tharani1, S Rajeshkumar2
1Centre for Transdisciplinary Research (CFTR), Nanobiomedicine Lab, Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Science, Saveetha University, Chennai, India.
Abstract:
A wound is a complicated health issue, and it severely affects the injured area because of the growth of many pathogenic microorganisms. Cinnamon and clove oil exhibit antibacterial activity against wound pathogens like Pseudomonas aeruginosa, Escherichia coli, and Klebsiella pneumoniae were identified by the disc diffusion method. Cinnamon and clove oils are effective antibacterial agents because of their importance in reducing virulence and pathogenicity of drug-resistant bacteria in vivo. The increased frequency in clinically observed cases of antibiotic resistance has been attributed to many factors, such as the misuse and overuse of antibiotics. In some countries, antibiotics are sold over the counter without a prescription; hence, this study aimed to investigate the antimicrobial effect of clove and cinnamon on clinically isolated resistant strains of P. aeruginosa, E. coli, and K. pneumoniae.
Related Concept Videos
Hand hygiene
Hand washing...
Antimicrobial Effectiveness
Surface Membrane Barriers
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
Defense Against Bacterial Pathogens
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
Antimicrobial Proteins
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
Gene Regulation in Microbial Communities: Quorum Sensing

