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Human neonatal and infant airway epithelial biology: the new frontier for developmental immunology

Gustavo Nino1, Maria J Gutierrez2, Carlos E Rodriguez-Martinez3

  • 1Children's National, Washington, USA.

Expert Review of Respiratory Medicine
|January 12, 2022
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Pediatricairway epitheliumneonatology

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Development of Immunocompetence01:22

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The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
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