Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

T and B lymphocytes in vitiligo.

J P Ortonne, A Alario

    Archives of Dermatological Research
    |April 7, 1978
    PubMed
    Summary

    This study found no significant differences in lymphocyte subpopulations between vitiligo patients and controls. These findings suggest lymphocytes may not play a role in vitiligo development.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Anterior segment angiography of the normal canine eye: a comparison between indocyanine green and sodium fluorescein.

    Veterinary journal (London, England : 1997)·2014
    Same author

    Development and validation of nail psoriasis quality of life scale (NPQ10).

    Journal of the European Academy of Dermatology and Venereology : JEADV·2010
    Same author

    What are melanocytes really doing all day long...?

    Experimental dermatology·2009
    Same author

    Melasma in Latin America: options for therapy and treatment algorithm.

    Journal of the European Academy of Dermatology and Venereology : JEADV·2009
    Same author

    A global survey of the role of ultraviolet radiation and hormonal influences in the development of melasma.

    Journal of the European Academy of Dermatology and Venereology : JEADV·2009
    Same author

    Imiquimod 5% cream for external genital or perianal warts in human immunodeficiency virus-positive patients treated with highly active antiretroviral therapy: an open-label, noncomparative study.

    The British journal of dermatology·2009

    Area of Science:

    • Immunology
    • Dermatology
    • Cell Biology

    Background:

    • Vitiligo is a complex skin depigmentation disorder.
    • The role of lymphocyte subpopulations in vitiligo pathogenesis remains unclear.
    • Understanding immune cell involvement is crucial for identifying potential therapeutic targets.

    Purpose of the Study:

    • To investigate potential differences in lymphocyte subpopulations between individuals with vitiligo and healthy controls.
    • To assess the involvement of specific lymphocyte subsets in the immune response related to vitiligo.

    Main Methods:

    • Studied lymphocyte subpopulations in 38 vitiligo patients and 44 healthy controls.
    • Utilized several immunological examinations, including E-RFC, EAC-RFC, EA-RFC, IF, and IF-elution.

    Main Results:

    • No significant differences were observed in the immunological parameters between the vitiligo group and the control group.
    • Specific assays for lymphocyte function (E-RFC, EAC-RFC, EA-RFC, IF, IF-elution) showed comparable results across both cohorts.

    Conclusions:

    • The results indicate that lymphocyte subpopulations are likely not implicated in the pathogenesis of vitiligo.
    • Further research may be needed to explore other immune mechanisms or factors contributing to vitiligo development.

    Related Experiment Videos