Diabetic Foot Infection with Bacteroides pyogenes
Padmaja Ananth Shenoy1, Shashidhar Vishwanath1, Ravikumar Terikere Nagaraj1
1Department of Microbiology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Journal of Global Infectious Diseases
|January 12, 2022
Summary
Diabetic foot infections can be serious. This case highlights a rare infection by Bacteroides pyogenes, an anaerobic bacterium typically found in animal bites, in a diabetic patient.
Area of Science:
- Microbiology
- Infectious Diseases
- Diabetology
Background:
- Diabetic foot infections (DFIs) are a major complication of diabetes mellitus.
- DFIs present a significant socioeconomic burden due to high morbidity and mortality.
- The microbiota in DFIs is typically polymicrobial, often involving Gram-negative aerobes and anaerobes.
Observation:
- This report details a rare case of a diabetic foot infection.
- The causative agent identified was *Bacteroides pyogenes*, an obligate anaerobic Gram-negative bacillus.
- This bacterium is more commonly associated with polymicrobial animal bite wound infections.
Findings:
- *Bacteroides pyogenes* can be a causative agent in diabetic foot infections.
- The presence of this specific anaerobic bacillus in a DFI is unusual.
- This finding expands the known spectrum of pathogens implicated in diabetic limb infections.
Implications:
- Clinicians should consider a broader range of anaerobic bacteria in DFIs, even those typically linked to other infection types.
- This case may prompt further research into the role of *Bacteroides pyogenes* in diabetic complications.
- Understanding the diverse microbial landscape of DFIs is crucial for effective treatment strategies.
Related Concept Videos
Bacterial Phylum Bacteroidota
187
The phylum Bacteroidota includes over 700 species classified into four primary orders: Bacteroidales, Cytophagales, Flavobacteriales, and Sphingobacteriales. These gram-negative, non-sporulating rods exhibit saccharolytic capabilities and can be aerobic or fermentative, encompassing obligate aerobes, facultative aerobes, and obligate anaerobes. Many species display gliding motility, though some are nonmotile or use flagella. The genus Bacteroides is well-studied due to its significant role in...
187
Acute Pyelonephritis II: Diagnostic Studies and Management
65
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
65
Bacterial Phylum Proteobacteria
217
Proteobacteria, one of the largest and most diverse bacterial phyla, encompasses a wide range of Gram-negative bacteria distinguished by their outer membrane composed of lipopolysaccharides. These microorganisms exhibit various metabolic capabilities, including phototrophy, chemolithotrophy, and heterotrophy, and thrive in diverse environments from soil to aquatic systems and host-associated niches. The phylum is divided into six classes: Alphaproteobacteria, Betaproteobacteria,...
217
Skin Diseases and Disorders
4.4K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
4.4K
Bacterial Phylum Spirochaetes
157
Spirochetes, unique bacteria in the phylum Spirochaetes, are gram-negative, motile, tightly coiled, slender, and flexible. They inhabit aquatic sediments and animals, with some causing diseases like syphilis. Spirochetes are classified into eight genera based on habitat, pathogenicity, phylogeny, and characteristics.Their distinctive motility arises from endoflagella, located within the cell’s periplasm. These endoflagella anchor at the cell poles and extend along the cell length, encased...
157
Acute Pyelonephritis I: Introduction
86
Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
86


