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Parkinson's Disease: Overview01:15

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Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
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Updated: Oct 7, 2025

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
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Parkinsonism: An emerging post COVID sequelae.

Abhijith Rajaram Rao1, Shaik Mohammed Hidayathullah2, Karan Hegde1

  • 1Department of Geriatric Medicine, Yenepoya Medical College Hospital, Mangalore, India.

Idcases
|January 12, 2022
PubMed
Summary

Post-COVID-19 infection can cause parkinsonism in older adults. This study observed three cases and their positive response to levodopa-carbidopa treatment for these new neurological symptoms.

Keywords:
COVID-19ParkinsonismPost COVID sequelae

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Area of Science:

  • Neurology
  • Infectious Diseases
  • Geriatrics

Background:

  • Parkinsonism is a complex neurological condition with various causes.
  • Post-viral infections have been recognized as a potential trigger for parkinsonism.
  • The COVID-19 pandemic has highlighted its widespread effects, including on the central nervous system.

Observation:

  • Three cases of parkinsonism following COVID-19 infection are presented.
  • All affected individuals were older adults, aged 60 years and above.
  • The onset of parkinsonian symptoms occurred after the viral infection.

Findings:

  • The reported cases demonstrate a link between COVID-19 and the development of parkinsonism.
  • Patients showed a positive response to treatment with levodopa-carbidopa.
  • This suggests a potential therapeutic avenue for post-COVID neurological sequelae.

Implications:

  • COVID-19 may represent a novel cause of secondary parkinsonism, particularly in the elderly.
  • Early recognition and treatment with dopaminergic agents like levodopa-carbidopa may improve outcomes.
  • Further research is warranted to understand the mechanisms and long-term effects of post-COVID parkinsonism.