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Updated: Oct 7, 2025

Transcanalicular Diode Laser-assisted Dacryocystorhinostomy for the Treatment of Primary Acquired Nasolacrimal Duct Obstruction
Published on: October 13, 2017
Co-existing lacrimal drainage anomalies in eyes with congenital Glaucoma
Sirisha Senthil1, Mohammad Javed Ali2, Raghava Chary1
1VST Centre for Glaucoma Care, L V Prasad Eye Institute, Hyderabad, India.
Insights
Congenital glaucoma (CG) co-occurs with congenital nasolacrimal duct obstruction (CNLDO) in 2.5% of young children, with simple CNLDO being most common. Early intervention for CNLDO is crucial to prevent infections and avoid delaying essential glaucoma surgery.
Area of Science:
- Ophthalmology
- Pediatric Ophthalmology
- Congenital Disorders
Background:
- Congenital glaucoma (CG) and congenital nasolacrimal duct obstruction (CNLDO) are common pediatric eye conditions.
- Co-occurrence of these conditions may impact management and outcomes.
- Understanding the prevalence and characteristics of co-existing CG and CNLDO is essential for comprehensive care.
Purpose of the Study:
- To determine the incidence of co-existing CNLDO and other lacrimal anomalies in infants with CG.
- To analyze the management strategies and treatment outcomes for this combined condition.
Main Methods:
- Retrospective analysis of children aged one year or younger diagnosed with CG and CNLDO between 1998 and 2019.
- Data collection included patient demographics, diagnostic findings, interventions, and treatment outcomes.
- Statistical analysis focused on prevalence, age at diagnosis, and success rates of interventions.
Main Results:
- The prevalence of CNLDO in infants with CG was 2.5% (51/1993).
- Simple CNLDO was observed in 93.1% of affected eyes, with complex CNLDO in 6.9%.
- Lacrimal probing had a 95.8% success rate; complex cases required Dacryocystorhinostomy (DCR).
- Glaucoma surgery was performed with a median delay of 18 days after lacrimal probing.
Conclusions:
- Co-existing lacrimal drainage anomalies, primarily simple CNLDO, are present in 2.5% of infants with CG.
- Prompt management of CNLDO is vital to prevent sight-threatening infections and expedite glaucoma surgery.
- Lacrimal probing is highly effective, while complex CNLDO necessitates DCR.
Aim:
To evaluate the occurrence of co-existing congenital nasolacrimal duct obstruction (CNLDO) and other lacrimal anomalies in eyes with congenital glaucoma (CG).
Methods:
Retrospective analysis of children aged ≤1-year with co-existing CG and CNLDO seen between 1998 and 2019, treatment interventions and outcomes.
Results:
During the study period, 1993 children had CG and 6203 children had CNLDO, among the children aged 1-year or less. Of these, 51 children (73 eyes) had co-existing CG and CNLDO. The prevalence of CNLDO in CG was 2.5% (51/1993) and the prevalence of CG among CNLDO was 0.8% (51/6203). Median age (Interquartile range, IQR) was 53 days (IQR: 8, 155), when they were diagnosed with CG. Among the children with CNLDO, 68 eyes (93.1%) had simple CNLDO, and 5 eyes (6.9%) had complex CNLDO. Associated lacrimal anomalies were present in 7/73 eyes, including congenital lacrimal fistula in two eyes, upper punctal agenesis and upper mid-canalicular obstruction in two eyes each, and upper single canalicular-wall hypoplasia in one eye. Lacrimal syringing and probing were successful in 69/72 eyes (95.8%), and failed in 3 eyes (4.2%). These 3 eyes had complex CNLDO and underwent Dacryocystorhinostomy (DCR) with Mitomycin-C and intubation. Sixty-two eyes underwent combined trabeculotomy and trabeculectomy, and two eyes underwent trabeculectomy. Median age at glaucoma surgery was 87 days (IQR: 54, 193). Median time delay for glaucoma surgery after probing was 18 days (IQR: 12, 35).
Conclusion:
Among children aged ≤1-year presenting with congenital glaucoma coexisting lacrimal drainage anomalies was noted in 2.5% and simple CNLDO was the commonest. Early intervention is of paramount importance to prevent sight-threatening intraocular infection with CNLDO, and to minimize the delay of glaucoma surgery. The outcomes of lacrimal probing were excellent, however complex CNLDO required DCR.
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