Co-existing lacrimal drainage anomalies in eyes with congenital Glaucoma

Sirisha Senthil1, Mohammad Javed Ali2, Raghava Chary1

  • 1VST Centre for Glaucoma Care, L V Prasad Eye Institute, Hyderabad, India.

Insights

Congenital glaucoma (CG) co-occurs with congenital nasolacrimal duct obstruction (CNLDO) in 2.5% of young children, with simple CNLDO being most common. Early intervention for CNLDO is crucial to prevent infections and avoid delaying essential glaucoma surgery.

Area of Science:

  • Ophthalmology
  • Pediatric Ophthalmology
  • Congenital Disorders

Background:

  • Congenital glaucoma (CG) and congenital nasolacrimal duct obstruction (CNLDO) are common pediatric eye conditions.
  • Co-occurrence of these conditions may impact management and outcomes.
  • Understanding the prevalence and characteristics of co-existing CG and CNLDO is essential for comprehensive care.

Purpose of the Study:

  • To determine the incidence of co-existing CNLDO and other lacrimal anomalies in infants with CG.
  • To analyze the management strategies and treatment outcomes for this combined condition.

Main Methods:

  • Retrospective analysis of children aged one year or younger diagnosed with CG and CNLDO between 1998 and 2019.
  • Data collection included patient demographics, diagnostic findings, interventions, and treatment outcomes.
  • Statistical analysis focused on prevalence, age at diagnosis, and success rates of interventions.

Main Results:

  • The prevalence of CNLDO in infants with CG was 2.5% (51/1993).
  • Simple CNLDO was observed in 93.1% of affected eyes, with complex CNLDO in 6.9%.
  • Lacrimal probing had a 95.8% success rate; complex cases required Dacryocystorhinostomy (DCR).
  • Glaucoma surgery was performed with a median delay of 18 days after lacrimal probing.

Conclusions:

  • Co-existing lacrimal drainage anomalies, primarily simple CNLDO, are present in 2.5% of infants with CG.
  • Prompt management of CNLDO is vital to prevent sight-threatening infections and expedite glaucoma surgery.
  • Lacrimal probing is highly effective, while complex CNLDO necessitates DCR.
Abstract

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