Crossreactivity of anti Lyt-2.2 monoclonal antibody with some Lyt-2.2-negative mouse strains
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P Kuśnierczyk1, A Opolski, M Seshadri
1Laboratory of Cellular Immunology, Polish Academy of Sciences, Wrocław.
Archivum Immunologiae Et Therapiae Experimentalis
|January 1, 1987
Abstract:
We observed that thymocytes from some Ly-2a (i.e., Lyt-2.2-) mouse strains crossreacted with high concentrations of anti Lyt-2.2 monoclonal antibody HO.2.2, whereas other Ly-2a strains were clearly negative. Inbred strains from two breeding colonies (Wrocław and Bombay) exhibited the same pattern of reactivity with HO.2.2. The nature of crossreacting antigen is discussed.