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Related Experiment Video

Updated: Oct 7, 2025

Multimodal 3D Printing of Phantoms to Simulate Biological Tissue
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Multimodal 3D Printing of Phantoms to Simulate Biological Tissue

Published on: January 11, 2020

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Screen Printing to Create 3D Tissue Models.

Narendra Pandala1, Sydney Haywood1, Michael A LaScola1

  • 1Chemical, Biochemical and Environmental Engineering, University of Maryland, Baltimore County, Baltimore, Piscataway Territories, Maryland 21250, United States.

ACS Applied Bio Materials
|January 12, 2022
PubMed
Summary

Screen printing offers an affordable and gentle method for creating 3D tissue models. This technique enables the precise deposition of live cells and scaffolds for advanced in vitro models.

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Area of Science:

  • Biotechnology
  • Tissue Engineering
  • Additive Manufacturing

Background:

  • Traditional 3D bioprinting methods can be costly and employ cell-damaging forces.
  • Existing techniques present limitations in material choice and substrate compatibility.

Purpose of the Study:

  • To develop and evaluate screen printing as an accessible alternative for creating in vitro tissue models.
  • To assess the feasibility of printing live cells and scaffolds using screen printing technology.

Main Methods:

  • Developed a novel screen printing process for live cells and bioinks.
  • Utilized a screen assembly to pattern cells and scaffold materials onto various surfaces.
  • Investigated the resolution, feature limits, and cellular viability post-printing.
Keywords:
3D modelsbioprintingin vitro modelslayered printingscreen printing

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Main Results:

  • Screen printing demonstrated a cost-effective and user-friendly approach.
  • The method allows for a wide range of bioinks and printing on diverse substrates.
  • Autoclavable components enhance the practicality of the system.

Conclusions:

  • Screen printing is a viable and advantageous technique for generating in vitro tissue models.
  • This method overcomes limitations of traditional bioprinting, offering broader applicability and reduced cost.