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Torulopsis glabrata endophthalmitis after keratoplasty with an organ-cultured cornea
Archives of Ophthalmology (Chicago, Ill. : 1960)
|June 1, 1978
Abstract:
Fungal endophthalmitis developed in an elderly woman following penetrating keratoplasty with an organ-cultured cornea. An unsuccessful search was made for the source of the infection. Modification in our sterility checks prior to surgery were made in hopes of preventing future infections.
Insights
Fungal endophthalmitis occurred in an elderly patient after a corneal transplant using an organ-cultured cornea. Sterility checks were enhanced to prevent future post-keratoplasty infections.
Area of Science:
- Ophthalmology
- Microbiology
Background:
- Corneal transplantation, or penetrating keratoplasty, is a common procedure to restore vision.
- Organ-cultured corneas are utilized for transplantation, requiring stringent sterility.
- Fungal endophthalmitis is a severe intraocular infection that can lead to vision loss.
Observation:
- An elderly female patient developed fungal endophthalmitis post-penetrating keratoplasty.
- The cornea used was organ-cultured.
- The source of fungal contamination was not identified despite an extensive search.
Findings:
- The case highlights a rare but serious complication of fungal endophthalmitis following corneal transplantation.
- The organ-culture method of cornea preservation did not prevent the infection.
- Despite efforts, the specific source of fungal inoculation remained elusive.
Implications:
- Reinforces the critical need for meticulous sterility protocols in organ-culture media and surgical procedures.
- Suggests potential for unidentified contamination sources in organ-cultured donor corneas.
- Emphasizes the importance of prompt diagnosis and management of endophthalmitis after keratoplasty.