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ProSynAR: a reference aware read merger
Benjamin Crysup1, Bruce Budowle1, August E Woerner1
1Center for Human Identification, University of North Texas, Fort Worth, TX 76107, USA.
Motivation:
Read-merging algorithms that look solely at the reads can misalign and mis-merge the reads (especially near repetitive sequences).
Results:
The C++ program ProSynAR has been written to take the reads' position in the reference into account when performing (and deciding whether to perform) a merge.
Availability:
*Nix users can retrieve the source from GitHub (https://github.com/Benjamin-Crysup/prosynar). Windows binary available at https://github.com/Benjamin-Crysup/prosynar/releases/download/1.0/prosynar.zip.
Supplementary Information:
Supplementary data are available at Bioinformatics online.
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