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Related Concept Videos

Pneumothorax-II01:27

Pneumothorax-II

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Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
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As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
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Related Experiment Video

Updated: Oct 6, 2025

Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation
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Published on: October 11, 2024

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Is high age a contraindication to pulmonary resection?

P Horák, M Kengbaeva, J Doležal

    Rozhledy V Chirurgii : Mesicnik Ceskoslovenske Chirurgicke Spolecnosti
    |January 13, 2022
    PubMed
    Summary

    Elderly patients undergoing pulmonary resection for lung cancer face similar complication rates to younger patients. Careful preoperative assessment ensures safety for seniors receiving standard surgical treatment, like lobectomy.

    Keywords:
    complicationcomplicationsgeriatric patientmortalitypulmonary resection

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    Area of Science:

    • Thoracic Surgery
    • Geriatric Oncology
    • Pulmonary Medicine

    Background:

    • Aging global population leads to increased diagnoses of operable primary pulmonary malignancy in elderly patients.
    • Pulmonary resection is a common treatment for lung cancer and other thoracic lesions.
    • Evaluating post-operative outcomes in elderly surgical patients is crucial.

    Purpose of the Study:

    • To assess and compare post-operative outcomes in elderly patients undergoing pulmonary resection versus younger patients.
    • To determine the safety and efficacy of standard surgical treatments for lung cancer in seniors.

    Main Methods:

    • Retrospective analysis of 424 patients undergoing anatomical pulmonary resection (2011-2020).
    • Comparison of open procedures (328) versus VATS lobectomy (96).
    • Evaluation of 30-day morbidity and mortality using a modified Clavien-Dindo classification across age subgroups (under 55, 55-64, 65-74, 75+).

    Main Results:

    • No statistically significant difference in complication rates was observed between age groups (p=0.220).
    • Standard surgical treatment, including lobectomy with mediastinal lymphadenectomy, demonstrated safety in well-indicated elderly patients.

    Conclusions:

    • Standard lobectomy with lymphadenectomy is safe for selected elderly patients with non-small cell lung carcinoma.
    • Comparable complication rates can be achieved in elderly patients through careful preoperative assessment and tailored resection extent.
    • Sublobar resection or radiotherapy may be considered for high-risk elderly patients; comparable oncological outcomes are achievable for seniors over 70, considering life expectancy.