Anetoderma in a Patient with Newly Diagnosed Hodgkin's Lymphoma

A previously healthy 28-year-old woman was admitted to the hospital with respiratory failure and was found to have significant lymphadenopathy on her CT scan. A lymph node biopsy was performed; the pathology was consistent with a diagnosis of Hodgkin's lymphoma and the patient was noted to have multiple, wrinkled, nonscaly, oval-shaped papules that were easily compressible (Figure 1) and were present on the upper and lower extremities, abdomen, chest, and back. The lesions were entirely asymptomatic and had first developed 1 year prior to presentation. Since their initial development, the wrinkled papules had continued to crop up. Some of the lesions began as brownish-red papules and subsequently turned skin-colored.Punch biopsies of the lesional and unaffected skin were performed. A Verhoeff-Van Gieson (VVG) stain showed loss of dermal elastic tissue in the lesional skin, compared to that of the unaffected skin. The clinical and histologic examinations were consistent with the diagnosis of anetoderma.