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Systemic and Local Drug Delivery for Treating Diseases of the Central Nervous System in Rodent Models
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Transdermal Nutraceuticals Delivery System for CNS Disease
Mohammed Asadullah Jahangir1, Pooja Jain2, Rishabh Verma2
1Department of Pharmaceutics, Nibha Institute of Pharmaceutical Sciences, Rajgir, Nalanda-803116, Bihar, India.
CNS & Neurological Disorders Drug Targets
|January 13, 2022
Summary
Nutraceuticals, derived from herbal medicines, offer effective, low-toxicity treatments for brain disorders. Transdermal delivery systems enhance their bioavailability and non-invasively target neurological conditions.
Area of Science:
- Pharmacology and Traditional Medicine
- Nanotechnology and Drug Delivery
- Neuroscience
Background:
- Herbal medicines have a long history of use, with growing scientific interest in nutraceuticals as alternatives to allopathic medicines.
- Nutraceuticals are gaining market acceptance due to their efficacy, low toxicity, and cost-effectiveness for various diseases.
- Improving the bioavailability and efficacy of herbal-derived nutraceuticals is crucial for their therapeutic application.
Purpose of the Study:
- To review the potential of nutraceuticals in treating brain-related disorders.
- To explore advancements in transdermal nano-systems for nutraceutical delivery.
- To highlight recent US patents indicating growing interest in transdermal nutraceuticals for brain health.
Main Methods:
- Literature review of nutraceuticals for neurological conditions.
- Analysis of transdermal drug delivery systems, specifically nano-systems.
- Examination of patent literature concerning transdermal nutraceuticals in the US.
Main Results:
- Transdermal delivery systems offer a non-invasive method to enhance nutraceutical bioavailability and bypass first-pass metabolism.
- Nutraceuticals show promise in managing various brain-related disorders.
- Emerging transdermal nano-systems are being developed for targeted delivery of these compounds.
Conclusions:
- Transdermal nutraceutical delivery systems present a significant advancement for treating brain disorders.
- These systems offer improved efficacy, targeted delivery, and patient convenience.
- The increasing patent activity underscores the therapeutic potential and commercial interest in this field.
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