Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Dimensions of Health and Illness01:21

Dimensions of Health and Illness

8.8K
The factors influencing the health-illness continuum can be internal or external and may or may not be under conscious control. They are related to the following eight human dimensions, and each dimension is interrelated to one other.
8.8K
Biological Effects of Radiation02:59

Biological Effects of Radiation

16.2K
All radioactive nuclides emit high-energy particles or electromagnetic waves. When this radiation encounters living cells, it can cause heating, break chemical bonds, or ionize molecules. The most serious biological damage results when these radioactive emissions fragment or ionize molecules. For example, α and β particles emitted from nuclear decay reactions possess much higher energies than ordinary chemical bond energies. When these particles strike and penetrate matter, they...
16.2K
Radiation: Applications01:17

Radiation: Applications

1.3K
The average temperature of Earth is the subject of much current discussion. Earth is in radiative contact with both the Sun and dark space; it receives almost all its energy from the radiation of the Sun and reflects some of it into outer space. Dark space is very cold, about 3 K, so Earth radiates energy into it. For instance, heat transfer occurs from soil and grasses, the rate of which can be so rapid that frost can occur on clear summer evenings, even in warm latitudes.
The average...
1.3K
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

191
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
191
Observational Studies01:11

Observational Studies

10.0K
Observational studies are a type of analytical study where researchers observe events without any interventions. In other words, the researcher does not influence the response variable or the experiment's outcome.
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
10.0K
Longitudinal Studies01:26

Longitudinal Studies

278
Longitudinal studies are also widely used in other medical and social science fields. For instance, in cardiovascular research, they can monitor patients' health over decades to identify risk factors for heart disease, such as high cholesterol or smoking, and evaluate the long-term effectiveness of preventive measures. Similarly, in mental health studies, researchers might follow individuals from adolescence into adulthood to understand the development and progression of conditions like...
278

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Utilizing the Life Span Study data in NASA astronaut cancer risk assessment.

Carcinogenesis·2025
Same author

Adverse Outcome Pathways Applied to Space Radiation Research.

Environmental and molecular mutagenesis·2025
Same author

Effect of fluorescence in situ hybridization detection threshold on chromosome aberration counting: a simulation study.

Life sciences in space research·2025
Same author

Considering clonal hematopoiesis of indeterminate potential in space radiation risk analysis for hematologic cancers and cardiovascular disease.

Communications medicine·2024
Same author

Galactic cosmic ray simulation at the NASA space radiation laboratory - Progress, challenges and recommendations on mixed-field effects.

Life sciences in space research·2023
Same author

Ionizing radiation, cerebrovascular disease, and consequent dementia: A review and proposed framework relevant to space radiation exposure.

Frontiers in physiology·2022

Related Experiment Video

Updated: Oct 6, 2025

Exploring the Effects of Spaceflight on Mouse Physiology using the Open Access NASA GeneLab Platform
11:08

Exploring the Effects of Spaceflight on Mouse Physiology using the Open Access NASA GeneLab Platform

Published on: January 13, 2019

12.5K

Earth-Based Research Analogs to Investigate Space-Based Health Risks.

Ronita L Cromwell1, Janice L Huff2, Lisa C Simonsen2

  • 1Baylor College of Medicine, Center for Space Medicine, Houston, Texas, USA.

New Space
|January 13, 2022
PubMed
Summary

Earth-based analogs are crucial for studying spaceflight hazards like radiation and isolation. These simulated environments help overcome limitations of space-based research, aiding astronaut health and performance for future missions.

Keywords:
ground analogshealth riskshuman spaceflight

More Related Videos

Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data
11:21

Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data

Published on: July 27, 2018

8.3K
Simulating Imaging of Large Scale Radio Arrays on the Lunar Surface
06:14

Simulating Imaging of Large Scale Radio Arrays on the Lunar Surface

Published on: July 30, 2020

5.0K

Related Experiment Videos

Last Updated: Oct 6, 2025

Exploring the Effects of Spaceflight on Mouse Physiology using the Open Access NASA GeneLab Platform
11:08

Exploring the Effects of Spaceflight on Mouse Physiology using the Open Access NASA GeneLab Platform

Published on: January 13, 2019

12.5K
Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data
11:21

Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data

Published on: July 27, 2018

8.3K
Simulating Imaging of Large Scale Radio Arrays on the Lunar Surface
06:14

Simulating Imaging of Large Scale Radio Arrays on the Lunar Surface

Published on: July 30, 2020

5.0K

Area of Science:

  • Space Medicine and Human Factors
  • Physiological and Behavioral Research
  • Spaceflight Analogs

Background:

  • Astronauts face unique spaceflight hazards: altered gravity, isolation, confinement, closed environments, and radiation exposure.
  • Maintaining human health and performance becomes increasingly challenging for long-duration missions beyond low Earth orbit.
  • Logistical issues, including high costs, time constraints, and small sample sizes, complicate space-based research.

Purpose of the Study:

  • To review the utilization of Earth-based analogs for simulating spaceflight environments and their associated hazards.
  • To highlight how analog studies contribute to understanding and mitigating risks for human space exploration.
  • To emphasize the importance of analogs in supporting future long-duration space missions and commercial space activities.

Main Methods:

  • Description of various Earth-based analog facilities (e.g., polar outposts, undersea laboratories).
  • Explanation of how these analogs replicate specific physiological and behavioral effects of spaceflight.
  • Discussion of the selection criteria for appropriate analogs based on research objectives.

Main Results:

  • Earth-based analogs provide a viable means to overcome logistical barriers inherent in space-based research.
  • Each analog offers unique simulation capabilities, allowing targeted investigation of specific spaceflight phenomena.
  • Analogs, while imperfect, are essential for augmenting space-based studies and gathering critical human factors data.

Conclusions:

  • Earth-based analogs are indispensable tools for advancing our understanding of human risks in space.
  • These simulated environments are vital for preparing astronauts and ensuring the success of future space endeavors.
  • Integrated research using both space-based platforms and analogs is necessary for pushing the frontiers of human spaceflight.