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Rapid identification of mcr-1-positive Escherichia coli from patient urine using a novel lipid-based MALDI-TOF-MS

Richard D Smith1,2, Jerilyn R Izac1,3, Michael Ha4

  • 1Department of Microbial Pathogenesis, School of Dentistry, University of Maryland Baltimore, Baltimore, MD, USA.

Access Microbiology
|January 13, 2022
PubMed

Keywords:
Escherichia coliMALDI-TOF MSmobilized colistin resistance geneurinary tract infection

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Mass spectrometry is a powerful characterization technique that can identify and separate a wide variety of compounds ranging from chemical to biological entities, based on their mass-to-charge ratio (m/z). The instruments that allow this detection, known as mass spectrometers, have three components: an ion source, a mass analyzer, and a detector. These spectrometers differ based on the nature of their ion source and analyzers.
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