Responsive DNA-Based Supramolecular Hydrogels
Jiezhong Shi1, Ziwei Shi2, Yuanchen Dong2
1Key Laboratory of Organic Optoelectronics & Molecular Engineering of the Ministry of Education, Department of Chemistry, Tsinghua University, Beijing 100084, China.
Abstract:
DNA supramolecular hydrogels are hydrogels cross-linked through DNA hybridization. They have attracted wide attention due to their great molecular permeability, biocompatibility, degradability, thixotropy, and self-healing properties, which make them very useful in cell culture, tissue engineering, and 3D printing. The designability and responsiveness of DNA endows these hydrogels with specific stimuli responsiveness, thus enhancing their utility for more applications, e.g., detection devices and shape-memory materials. In this review, we outlined and discussed the development of responsive DNA supramolecular hydrogels, and their applications have also been summarized.
