Impact of Heparin Preadministration for Detection of Prosthetic Valve Endocarditis With FDG PET/CT
Basak Soydas Turan1, M Fani Bozkurt
1From the Department of Nuclear Medicine, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
Abstract:
A 57-year-old woman with history of aortic and mitral valves replacement was referred to FDG PET/CT before valvular prosthesis renewal surgery. First FDG PET/CT was suboptimal for interpretation due to prominent physiological myocardial FDG uptake, despite patient preparation including 12 hours of fasting and low-carbohydrate, fat-rich diet. Therefore, scan was repeated with IV heparin preadministration at another day and revealed focal FDG uptake on the region of prosthetic heart valves, suggesting endocarditis. FDG PET/CT has been proven to be a useful technique to detect endocarditis, but appropriate patient preparation for adequate suppression of physiological myocardial uptake is important. Heparin preadministration seems to be an important component of patient preparation.
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