Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Assessing the knowledge, attitude, and practices of reproductive health schemes among tribal women in Jharkhand: A cross-sectional study.

BMC public health·2026
Same author

Surface reduction boosts free electron concentration in MXene for enhanced photothermal performance.

Science advances·2026
Same author

Screening of non-communicable diseases through health camps: A sustainable way to intercept the modern epidemic.

Journal of education and health promotion·2026
Same author

Breaking barriers: access to services among people living with HIV/AIDS (PLHIV) in Jharkhand - a convergent mixed methods study.

BMC public health·2026
Same author

Tobacco usage among healthcare professionals and workers in tribal areas of Jharkhand - A cross-sectional study.

Journal of education and health promotion·2026
Same author

Evaluation of risk factors for ocular morbidities and their impact on the lives of medical students: A cross-sectional study unveiling the academic collateral.

F1000Research·2026

Related Experiment Video

Updated: Oct 6, 2025

Laser-scanning Photostimulation of Optogenetically Targeted Forebrain Circuits
07:43

Laser-scanning Photostimulation of Optogenetically Targeted Forebrain Circuits

Published on: December 27, 2013

9.4K

Towards translational optogenetics.

Akshaya Bansal1, Swati Shikha1, Yong Zhang2,3,4

  • 1Department of Biomedical Engineering, Faculty of Engineering, National University of Singapore, Singapore, Singapore.

Nature Biomedical Engineering
|January 14, 2022
PubMed
Summary

Optogenetics uses light to control cell functions for disease research and therapy. Future tools aim for safer gene delivery and deeper tissue light penetration for clinical applications.

More Related Videos

Two Different Real-Time Place Preference Paradigms Using Optogenetics within the Ventral Tegmental Area of the Mouse
05:50

Two Different Real-Time Place Preference Paradigms Using Optogenetics within the Ventral Tegmental Area of the Mouse

Published on: February 12, 2020

13.8K
Bioluminescent Optogenetics 2.0: Harnessing Bioluminescence to Activate Photosensory Proteins In Vitro and In Vivo
07:19

Bioluminescent Optogenetics 2.0: Harnessing Bioluminescence to Activate Photosensory Proteins In Vitro and In Vivo

Published on: August 4, 2021

4.8K

Related Experiment Videos

Last Updated: Oct 6, 2025

Laser-scanning Photostimulation of Optogenetically Targeted Forebrain Circuits
07:43

Laser-scanning Photostimulation of Optogenetically Targeted Forebrain Circuits

Published on: December 27, 2013

9.4K
Two Different Real-Time Place Preference Paradigms Using Optogenetics within the Ventral Tegmental Area of the Mouse
05:50

Two Different Real-Time Place Preference Paradigms Using Optogenetics within the Ventral Tegmental Area of the Mouse

Published on: February 12, 2020

13.8K
Bioluminescent Optogenetics 2.0: Harnessing Bioluminescence to Activate Photosensory Proteins In Vitro and In Vivo
07:19

Bioluminescent Optogenetics 2.0: Harnessing Bioluminescence to Activate Photosensory Proteins In Vitro and In Vivo

Published on: August 4, 2021

4.8K

Area of Science:

  • Neuroscience
  • Biotechnology
  • Medical Engineering

Background:

  • Optogenetics is a powerful tool for studying neural circuits in diseases.
  • It has emerged as a promising therapeutic strategy.
  • The current optogenetic toolkit includes light-responsive proteins, gene delivery vectors, and light-delivery devices.

Purpose of the Study:

  • To review the current optogenetics toolkit.
  • To examine preclinical and translational applications of optogenetics.
  • To discuss future developments and challenges in optogenetics.

Main Methods:

  • Review of current optogenetic technologies.
  • Analysis of preclinical and translational studies.
  • Discussion of emerging methodologies and bottlenecks.

Main Results:

  • The optogenetic toolkit comprises light-sensitive proteins, gene vectors, and light-delivery systems.
  • Significant preclinical and translational applications have been demonstrated.
  • Advancements are needed in gene delivery, protein sensitivity, light penetration, and device technology.

Conclusions:

  • A refined optogenetic toolkit is crucial for translational success.
  • Future developments should focus on safer gene vectors, red-shifted proteins, enhanced light delivery, and wireless devices.
  • Overcoming methodological and translational bottlenecks is key for clinical impact.