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Optimized Analysis of In Vivo and In Vitro Hepatic Steatosis
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Optimized Analysis of In Vivo and In Vitro Hepatic Steatosis

Published on: March 11, 2017

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Alcoholic liver disease-from steatosis to cirrhosis - a biochemistry approach

Ruxandra Cioarca-Nedelcu1, Valeriu Atanasiu1, Irina Stoian1

  • 1Biochemistry Department, University of Medicine and Pharmacy Carol Davila, Bucharest, Romania.

Journal of Medicine and Life
|January 14, 2022
PubMed

Keywords:
-OH – hydroxyl radicalA(2)C – 2-(2-methoxy ethoxy) ethyl 8-(cis-2-n-octylcyclopropyl)ADH – alcohol dehydrogenaseALDH2 – aldehyde dehydrogenase 2AMPK – adenosine monophosphate-activated protein kinaseCD14 – cluster of differentiationCYP2E1 – cytochrome P450 2E1DNA – deoxyribonucleic acidER – endoplasmic reticulumGSH – glutathioneH2O2 – hydrogen peroxideHER – hydroxyethyl radicalHSC – hepatic stellate cellsJNK – Janus KinaseKC – Kupffer cellsLPS – lipopolysaccharidesMAA – malondialdehyde-acetaldehyde compoundsNAD+ – nicotinamide adenine dinucleotideNADH – reduced nicotinamide adenine dinucleotideNADP+ – nicotinamide adenine dinucleotide phosphateNADPH – reduced nicotinamide adenine dinucleotide phosphateO2-∙ – superoxide anionPPARalpha – peroxisome proliferator-activated receptor-alphaROS – reactive oxygen speciesSREBP-1 – sterol regulatory element-binding protein 1TLR4 – toll-like receptor 4TNFalpha – tumor necrosis factor-alphacirrhosisethanoloxidative stresssteatohepatitissteatosis

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