Research progress on negative pressure wound therapy with instillation in the treatment of orthopaedic wounds
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Updated: Oct 6, 2025

Development of a Benchtop Model for Evaluating the Compatibility of Wound Dressing Materials with Negative Pressure Wound Therapy Systems
Published on: May 2, 2025
Lijiao Wu1,2, Baoyu Wen1,2, Zhaorong Xu3
1Department of Orthopedic Surgery, Fujian Provincial Hospital Jinshan Branch, Fuzhou, China.
Abstract:
Negative pressure wound therapy with instillation (NPWTi) has the dual function of negative pressure sealing drainage and irrigation, which overcomes the disadvantages of NPWT, such as tube obstruction, inability to apply topical medicine, and poor anti-infection ability. NPWTi has been researched extensively and widely used in various types of wounds, and certain effects have been achieved. A series of parameters for NPWTi have not been unified at present, including the flushing fluid option, flushing mode, and treatment period. This paper reviews the research progress of these parameters for NPWTi and their application in the treatment of orthopaedic wounds.

