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Updated: Oct 6, 2025
Author Spotlight: Utilizing Traditional Chinese Acupuncture of the Ear to Improve Sleep Disorders
Published on: August 18, 2023
Effectiveness and safety of auricular therapy for post-stroke depression: A protocol for systematic review and
Mingzhi Tang1, Sisi Feng, Yihao Zhou
1Yunnan University of Traditional Chinese Medicine, Kunming, China.
Background:
Post-stroke depression is a common and serious complication after stroke. Its main clinical manifestations are depression or instability, loss of interest, loss of appetite, sleep disorders, pessimism, and unworthiness, and even suicidal tendencies. Auricular therapy (AT), as part of traditional Chinese acupuncture, has achieved good results in the treatment of depression, but different clinical studies have shown mixed results. Therefore, the aim of this systematic review is to assess the effectiveness and safety of AT for post-stroke depression.
Methods:
Two reviewers will electronically search the following databases: the Cochrane Central Register of Controlled Trials; Medline (via PubMed); Excerpt Medica Database; China National Knowledge Infrastructure; Chinese Biomedical Literature Database; Chinese Scientific Journal Database; and Wan-Fang Database from the inception to January 1, 2022. Study selection, data extraction, and assessment of study quality will be performed independently by 2 reviewers. If it is appropriate for a meta-analysis, Review Manager Version 5.3 statistical software will be used; otherwise, a descriptive analysis will be conducted. Data will be synthesized by either the fixed-effects or random-effects model according to a heterogeneity test. The results will be presented as risk ratio with 95% confidence intervals for dichotomous data and weight mean difference or standard mean difference 95% confidence intervals for continuous data.
Result:
This study will provide a comprehensive review of the available evidence for the treatment of AT with post-stroke depression.
Conclusions:
The conclusions of our study will provide an evidence to judge whether AT is an effective and safe intervention for patients with post-stroke depression.
Trial Registration Number:
PROSPERO CRD42021289870.
