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[Clinical impact of small bowell capsule endoscopy in obscure gastrointestinal bleeding : retrospective single-center
A C Moreau1, L Seidel1, S Vieujean1
1Service de Gastro-Entérologie, CHU Liège, Belgique.
Insights
Capsule endoscopy significantly changes management for obscure gastrointestinal bleeding (OGIB) patients, with a low rebleeding risk. However, some patients may not require this diagnostic tool, as indicated by a lack of therapeutic change or recurrence.
Area of Science:
- Gastroenterology
- Medical Diagnostics
Background:
- Small-bowel capsule endoscopy (VCE) is a validated tool for investigating obscure gastrointestinal bleeding (OGIB).
- Routine clinical practice evaluation of VCE for OGIB is essential.
Purpose of the Study:
- To assess the clinical impact of VCE in managing OGIB patients in a real-world setting.
- To determine the influence of VCE on subsequent patient management and rebleeding risk.
Main Methods:
- Retrospective analysis of 110 patients with OGIB undergoing VCE.
- Data collected at CHU of Liège between March 2016 and December 2019.
Main Results:
- Diagnostic yield for VCE was 58%.
- Therapeutic management changed in 39% of patients.
- Recurrence rate was 22.5% over 2 years; rebleeding risk was low with normal VCE or therapeutic modification. 45% had no change in management or recurrence.
Conclusions:
- VCE prompts therapeutic modification in approximately 40% of OGIB patients, associated with a low relapse rate.
- VCE may be avoidable in a subset of patients (45%) who experience no management change or recurrence.
Introduction:
The small-bowel capsule endoscopy (VCE) has been validated in the investigation of obscure gastrointestinal bleeding (OGIB). The aim of this study was to evaluate the clinical impact of VCE for OGIB in routine practice, in terms of subsequent management and the risk of rebleeding.
Methods:
Our retrospective study analyzed the VCE at the CHU of Liège from March 2016 to December 2019 (cohort of 110 patients with OGIB).
Results:
We found a diagnostic yield of 58 %, a change in therapeutic attitude in 39 % of patients and a recurrence rate of 22.5 % (out of 102 patients followed at 2 years). The rate of rebleeding was particularly low in patients with normal VCE and in those for whom a therapeutic modification was made. Finally, about 45 % of patients did not have any change in therapeutic attitude nor recurrence.
Conclusion:
VCE leads to a therapeutic modification in about 40 % of patients with a low risk of relapse. However, VCE could be avoided in some patients as evidenced by a subgroup representing 45 % of patients for whom there was no therapeutic modification nor recurrence.
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