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Updated: Oct 6, 2025
Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates
Published on: March 20, 2015
Depth prediction of nanotags in tissue using surface enhanced spatially offset Raman scattering (SESORS)
Matthew E Berry1, Samantha M McCabe1, Neil C Shand2
1Centre for Molecular Nanometrology, Department of Pure and Applied Chemistry, University of Strathclyde, 99 George Street, Glasgow, G1 1RD, UK. karen.faulds@strath.ac.uk.
Abstract:
A model for the prediction of the depth of two 'flavours' of surface enhanced Raman scattering (SERS) active nanotags embedded within porcine tissue is demonstrated using ratiometric analysis. Using a handheld spatially offset Raman (SORS) instrument, SESORS signals could be detected from nanotags at depths down to 48 mm for the first time using a backscattering SORS geometry.
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