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A review on AI in PET imaging
Keisuke Matsubara1, Masanobu Ibaraki1, Mitsutaka Nemoto2
1Department of Radiology and Nuclear Medicine, Research Institute for Brain and Blood Vessels, Akita Cerebrospinal and Cardiovascular Center, Akita, Japan.
Annals of Nuclear Medicine
|January 14, 2022
Summary
Deep learning, including convolutional neural networks (CNNs) and generative adversarial networks (GANs), enhances medical imaging. This review categorizes deep learning applications in positron emission tomography (PET) image generation, focusing on denoising, reconstruction, and synthesis.
Area of Science:
- Medical Imaging
- Artificial Intelligence
- Radiology
Background:
- Artificial intelligence (AI) is increasingly used in medical imaging for tasks like computer-aided diagnosis.
- Deep learning techniques, specifically CNNs and GANs, are prominent in medical image generation.
- Previous research has explored deep learning for generating images using positron emission tomography (PET).
Purpose of the Study:
- To review studies applying deep learning techniques for image generation in PET.
- To categorize existing research into key themes of PET image generation using deep learning.
- To discuss limitations and future directions for deep learning in PET image generation.
Main Methods:
- Literature review of studies utilizing deep learning for PET image generation.
- Categorization of reviewed studies into three main themes: denoising, reconstruction/attenuation correction, and image translation/synthesis.
- Analysis of recent advancements and methodologies within each category.
Main Results:
- Deep learning effectively aids in denoising noisy PET data to recover full information.
- AI techniques show promise in PET image reconstruction and attenuation correction.
- Deep learning facilitates PET image translation and synthesis, expanding imaging capabilities.
Conclusions:
- Deep learning offers significant potential for advancing PET image generation across various applications.
- Further research is needed to address the limitations and fully realize the future prospects of AI in PET imaging.
- The reviewed categories highlight the diverse and evolving role of deep learning in PET.

