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Imaging of Peritoneal Dialysis Complications in Children
Eman Marie1, María Navallas1, Elizabeth Harvey1
1From the Department of Diagnostic Imaging, McMaster Children's Hospital, McMaster University, 1200 Main St W, Hamilton, ON, Canada L8N 3Z5 (E.M.); Department of Diagnostic Imaging, Hospital Universitario 12 de Octubre, Madrid, Spain (M.N.); Department of Pediatrics, Division of Nephrology (E.H.); Department of Surgery, Division of Urology (A.J.L.); and Department of Diagnostic Imaging (K.O.), Division of Nuclear Medicine (R.V., A.S.), The Hospital for Sick Children, Toronto, ON, Canada; Department of Medical Imaging, University of Toronto, Toronto, ON, Canada (R.V., K.O., A.S.); and Great Ormond Street Hospital for Children, NHS, London, England (S.D.).
Insights
Peritoneal dialysis (PD) is crucial for children with end-stage renal disease. Imaging aids in diagnosing PD complications, ensuring effective treatment and preventing technique failure.
Area of Science:
- Pediatric Nephrology
- Radiology
- Renal Replacement Therapy
Background:
- Peritoneal dialysis (PD) is a primary renal replacement therapy for pediatric end-stage renal disease awaiting transplantation.
- PD involves a catheter for solution exchange across the peritoneal membrane, vital for waste removal.
- Complications can lead to technique failure and a switch to hemodialysis.
Purpose of the Study:
- To review the role of imaging in diagnosing peritoneal dialysis complications in children.
- To describe the benefits and limitations of various imaging modalities for PD complications.
- To familiarize radiologists with radiologic findings for early diagnosis and management.
Main Methods:
- Review of imaging techniques including radiography, ultrasound (US), CT, MRI, and peritoneal scintigraphy.
- Analysis of radiologic findings associated with common PD complications.
- Discussion of the role of imaging in guiding clinical management decisions.
Main Results:
- Imaging is instrumental in the prompt diagnosis and management of PD complications.
- Each modality (radiography, US, CT, MRI, scintigraphy) offers unique benefits and limitations.
- Familiarity with radiologic findings aids in early detection and appropriate patient management.
Conclusions:
- Radiologists play a crucial role in the early diagnosis of PD complications.
- Accurate imaging facilitates tailored PD management or timely transition to hemodialysis.
- Effective diagnosis and management of PD complications are key to preserving technique survival.
Abstract:
Worldwide, peritoneal dialysis (PD) is the preferred renal replacement therapy option for children with end-stage renal disease who are awaiting transplantation. PD involves the instillation of a specifically formulated solution into the peritoneal cavity via a PD catheter, with two-way exchange of solutes and waste products along a concentration gradient. This exchange occurs across the peritoneal membrane. The PD catheter has intraperitoneal, abdominal wall, and external components. Enormous efforts have been directed to augment the efficiency and longevity of the peritoneum as a dialysis system by preventing PD-related infectious and noninfectious complications, which may otherwise result in technique failure and a subsequent temporary or permanent switch to hemodialysis. Imaging has an instrumental role in prompt diagnosis of PD complications and in guiding the management of these complications. The main imaging techniques used in the setting of PD complications-namely, conventional radiography, US, CT, MRI, and peritoneal scintigraphy-as well as the benefits and limitations of these modalities are reviewed. The authors also describe the frequently encountered radiologic findings of each complication. Familiarity with these features enables the radiologist to play a crucial role in early diagnosis of PD complications and aids the pediatric nephrologist in tailoring or discontinuing PD and transitioning to hemodialysis if necessary. Online supplemental material is available for this article. ©RSNA, 2022.
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