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Updated: Oct 6, 2025

Quantification of Metal Leaching in Immobilized Metal Affinity Chromatography
Published on: January 17, 2020
Development of a metal sieve-linked double syringe liquid phase microextraction method for the determination of
Tuğçe Unutkan Gösterişli1, İrem Zehra Kublay2, Sude Oflu2
1Yıldız Technical University, Department of Chemical Engineering, 34349 İstanbul, Turkey.
Abstract:
This work reports the development of a simple, sensitive and low-cost analytical method for the trace determination of copper. A metal sieve-linked double syringe liquid phase microextraction method was used to preconcentrate copper into measurable quantities for FAAS system. The pressurized mixing offered by the automated syringe system and the sieve connector enhanced surface area for analyte and extraction solvent interaction, this significantly increased the extraction efficiency for copper. There was therefore no need for auxiliary organic solvents as disperser solvents for the extractant dichloromethane. The limits of detection and quantification, linear dynamic range and percent relative standard deviation values calculated for copper under optimum conditions of the method were 1.5 and 5.1 µg L-1, 5.0-500 µg L-1 and 8.4%, respectively. The developed method was successfully employed to determine copper (0.75-8.06 mg kg-1) in unspiked olive leaf samples.
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