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Rational Construction of Highly Tunable Organic Charge-Transfer Complexes for Chemiresistive Sensor Applications.

Jinming Chen^1,2, Mingzhu Yan^1,2, Yilong Tang^1,2

¹State Key Lab of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Changning Road 865, Shanghai 200050, China.

ACS Applied Bio Materials

|January 15, 2022

Summary

Researchers developed a novel organic charge-transfer (CT) complex sensor for detecting nerve agent mimics like diethyl chlorophosphate (DCP). This highly selective sensor achieves rapid, room-temperature detection at sub-parts per billion levels.

Keywords:

charge-transfer degree chemiresistive sensors nerve agents organic charge-transfer complexes organic electronics solution processability

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Area of Science:

Materials Science
Chemical Sensing
Organic Electronics

Background:

Organic charge-transfer (CT) complexes offer unique electrical properties for organic electronics.
Rational design of CT complexes for practical applications remains a significant challenge.
Developing sensitive and selective chemical sensors is crucial for safety and security.

Purpose of the Study:

To rationally design a chemiresistive sensor for nerve agent mimic detection using organic CT complexes.
To investigate the influence of morphology and intermolecular interactions on sensor performance.
To explore the potential of CT complexes for flexible and wearable biosensor applications.

Main Methods:

Design and synthesis of organic CT complexes.
Fabrication of chemiresistive sensors.
Vapor detection experiments using diethyl chlorophosphate (DCP) as a mimic.
Analysis of sensor response, selectivity, and kinetics.
Investigation of structure-property relationships (morphology, intermolecular interactions).

Main Results:

A CT complex-based chemiresistive sensor achieved sub-ppb detection of DCP within 5 seconds.
The sensor demonstrated high selectivity under ambient conditions (room temperature, atmospheric pressure).
Stronger intermolecular interactions correlated with lower sensing responses in CT complexes with varied donor/acceptor combinations.
The study elucidated the impact of morphology and intermolecular forces on sensing performance.

Conclusions:

Rationally designed organic CT complexes provide a highly tunable platform for effective chemiresistive sensing.
The developed sensor offers rapid, selective, and sensitive detection of nerve agent mimics.
Organic CT materials' inherent properties (solution processability, flexibility) open avenues for advanced flexible and wearable biosensors.