Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mechanistic Models: Overview of Compartment Models01:21

Mechanistic Models: Overview of Compartment Models

191
Mechanistic models, a category encompassing both physiological and compartmental modeling, differ from empirical models' approaches to incorporating known factors about the systems being modeled. Empirical models describe data with minimal assumptions, while mechanistic models aim to provide a robust description of available data by specifying assumptions and integrating known factors about the system. Compartmental analysis is a key example of a mechanistic model in pharmacokinetics and...
191
Mechanistic Models: Compartment Models in Individual and Population Analysis01:23

Mechanistic Models: Compartment Models in Individual and Population Analysis

100
Mechanistic models are utilized in individual analysis using single-source data, but imperfections arise due to data collection errors, preventing perfect prediction of observed data. The mathematical equation involves known values (Xi), observed concentrations (Ci), measurement errors (εi), model parameters (ϕj), and the related function (ƒi) for i number of values. Different least-squares metrics quantify differences between predicted and observed values. The ordinary least...
100
Neural Circuits01:25

Neural Circuits

1.8K
Neural circuits and neuronal pools are two of the main structures found in the nervous system. Neural circuits are networks of neurons that work together to carry out a specific task or process. They consist of interconnected neurons and glial cells, which provide structural and metabolic support.
Neuronal pools are collections of nerve cells with similar functions and interact through chemical and electrical signals. These pools include both interneurons (the central neural circuit nodes that...
1.8K
Sequence Networks of Rotating Machines01:24

Sequence Networks of Rotating Machines

167
A Y-connected synchronous generator, grounded through a neutral impedance, is designed to produce balanced internal phase voltages with only positive-sequence components. The generator's sequence networks include a source voltage that is exclusively in the positive-sequence network. The sequence components of line-to-ground voltages at the generator terminals illustrate this configuration.
Zero-sequence current induces a voltage drop across the generator's neutral impedance and other...
167
Clearance Models: Physiological Models01:09

Clearance Models: Physiological Models

139
Drug clearance is a critical pharmacokinetic process involving the irreversible removal of drugs from the body through various organs over a specified time period. Physiological models are indispensable in determining organ-specific clearance, defined by the proportion of the drug eliminated per unit of time from the organ's blood volume.
The organ's clearance rate depends on the blood flow to the organ and the extraction ratio (E). The extraction ratio describes the organ's...
139
Per-Unit Sequence Models01:26

Per-Unit Sequence Models

140
An ideal Y-Y transformer, grounded through neutral impedances, displays per-unit sequence networks akin to those of a single-phase ideal transformer when subjected to balanced positive- or negative-sequence currents. These currents do not produce neutral currents, and their associated voltage drops.
Zero-sequence currents, which are identical in magnitude and phase, generate a neutral current, resulting in voltage drops across the neutral impedance and the low-voltage winding. If the...
140

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Optimization strategies to obtain smooth gait transitions through biologically plausible central pattern generators.

Physical review. E·2024
Same author

[Lipofilling in the management of breast cancer: An update based on a literature review and national and international guidelines].

Gynecologie, obstetrique, fertilite & senologie·2023
Same author

[Breast cancer and organ transplantation: Systematic review and meta-analysis].

Gynecologie, obstetrique, fertilite & senologie·2022
Same author

3D-printed simulator for nasopharyngeal swab collection for COVID-19.

Infectious diseases now·2022
Same author

[Techniques and complications of non-genetic risk reducing mastectomies: Guidelines of the National College of French Gynecologists and Obstetricians (CNGOF)].

Gynecologie, obstetrique, fertilite & senologie·2021
Same author

[Connected bras for breast cancer detection in 2021: Analysis and perspectives].

Gynecologie, obstetrique, fertilite & senologie·2021

Related Experiment Video

Updated: Oct 6, 2025

Optical Imaging of Neurons in the Crab Stomatogastric Ganglion with Voltage-sensitive Dyes
09:36

Optical Imaging of Neurons in the Crab Stomatogastric Ganglion with Voltage-sensitive Dyes

Published on: March 23, 2011

13.2K

Towards more biologically plausible central-pattern-generator models.

V Baruzzi1, M Lodi1, M Storace1

  • 1Department of Electrical, Electronics and Telecommunication Engineering and Naval Architecture, University of Genoa, 16145 Genoa, Italy.

Physical Review. E
|January 15, 2022
PubMed
Summary

This study introduces a new method for designing central pattern generator (CPG) models. The method uses synaptic plasticity to enable biologically plausible gait transitions in quadruped locomotion simulations.

More Related Videos

Homarus Americanus Stomatogastric Nervous System Dissection
26:22

Homarus Americanus Stomatogastric Nervous System Dissection

Published on: May 28, 2009

11.3K
Inherent Dynamics Visualizer, an Interactive Application for Evaluating and Visualizing Outputs from a Gene Regulatory Network Inference Pipeline
10:44

Inherent Dynamics Visualizer, an Interactive Application for Evaluating and Visualizing Outputs from a Gene Regulatory Network Inference Pipeline

Published on: December 7, 2021

2.3K

Related Experiment Videos

Last Updated: Oct 6, 2025

Optical Imaging of Neurons in the Crab Stomatogastric Ganglion with Voltage-sensitive Dyes
09:36

Optical Imaging of Neurons in the Crab Stomatogastric Ganglion with Voltage-sensitive Dyes

Published on: March 23, 2011

13.2K
Homarus Americanus Stomatogastric Nervous System Dissection
26:22

Homarus Americanus Stomatogastric Nervous System Dissection

Published on: May 28, 2009

11.3K
Inherent Dynamics Visualizer, an Interactive Application for Evaluating and Visualizing Outputs from a Gene Regulatory Network Inference Pipeline
10:44

Inherent Dynamics Visualizer, an Interactive Application for Evaluating and Visualizing Outputs from a Gene Regulatory Network Inference Pipeline

Published on: December 7, 2021

2.3K

Area of Science:

  • Neuroscience
  • Robotics
  • Computational Biology

Background:

  • Central pattern generators (CPGs) are neural networks crucial for rhythmic motor activities like locomotion.
  • Understanding CPGs is key to developing bio-inspired robots and prosthetic devices.
  • Existing CPG models often struggle with dynamic gait transitions.

Purpose of the Study:

  • To develop a systematic method for designing CPG models.
  • To enable biologically plausible gait transitions using short-term synaptic plasticity.
  • To validate the method using a quadruped locomotion model.

Main Methods:

  • A novel method for CPG model design was defined.
  • Short-term synaptic plasticity mechanisms were implemented.
  • A CPG model for quadruped locomotion was created and tested.

Main Results:

  • The designed CPG model successfully reproduced three out of four standard quadruped gaits.
  • Gait reproduction accuracy extended to limb sequence, frequency, duty cycle, and phase lags.
  • The model demonstrated biologically plausible gait transitions.

Conclusions:

  • The proposed method effectively designs CPGs capable of realistic gait transitions.
  • Short-term synaptic plasticity is a viable mechanism for achieving dynamic locomotion control in CPGs.
  • This approach advances the development of sophisticated bio-inspired locomotion systems.