Delayed Gastric Emptying After Multivisceral Resection for Retroperitoneal Sarcoma

Area of Science:

• Surgical Oncology
• Gastroenterology
• Clinical Outcomes Research

Background:

• Delayed gastric emptying (DGE) is a frequent surgical complication.
• Its incidence and significance after multivisceral resection remain unclear.

Purpose of the Study:

• To determine the incidence and clinical relevance of DGE following multivisceral resection for retroperitoneal sarcoma (RPS).
• To identify risk factors and associated morbidities of DGE in this patient population.

Main Methods:

• Analysis of 100 consecutive patients with primary RPS undergoing multivisceral resection.
• DGE grading based on International Study Group of Pancreatic Surgery criteria; primary vs. secondary DGE classification.
• Assessment of patient, tumor, and treatment characteristics, and postoperative morbidity (Clavien-Dindo grade ≥ 3).

Main Results:

• Clinically relevant DGE (grades B-C) occurred in 28% of patients.
• Secondary DGE was frequently associated with infections, pancreatic leaks, and bowel leaks.
• DGE correlated with increased hospital stay, ICU admission, postoperative complications, and re-operation.
• Independent risk factors for DGE included patient comorbidities and tumor size.

Conclusions:

• Delayed gastric emptying is a significant and clinically relevant complication after multivisceral resection.
• Underlying complications frequently precipitate DGE, necessitating prompt diagnosis and management.
• Timely treatment of DGE and associated complications ensures full patient recovery.