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Updated: Oct 6, 2025

Author Spotlight: Revolutionizing Microfluidics Through Microchannel Fabrication on Nanopaper
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Paper based micro/nanofluidics devices for biomedical applications.

P E Resmi1, P V Suneesh2, T Ramachandran3

  • 1Amrita Biosensor Research Lab, Amrita School of Engineering Coimbatore, Amrita Vishwa Vidyapeetham, Coimbatore, India.

Progress in Molecular Biology and Translational Science
|January 16, 2022
PubMed
Summary

This chapter explores paper-based microfluidic devices, covering their importance, fabrication, and biomedical uses. It highlights diagnostic applications and discusses current challenges and future research directions in paper microfluidics.

Keywords:
Clinical diagnosisDipsticksLateral flow assayMicroPADsPaper-based analytical devices

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Area of Science:

  • Biomedical Engineering
  • Analytical Chemistry
  • Materials Science

Background:

  • Paper-based microfluidic devices offer a low-cost, accessible platform for diagnostics.
  • Key components include pretreatment methods, dipsticks, lateral flow assays, and microfluidic paper-based analytical devices (µPADs).

Purpose of the Study:

  • To detail the significance, fabrication, and biomedical applications of paper-based microfluidic devices.
  • To provide a comprehensive overview of paper diagnostic technologies.

Main Methods:

  • Review of fabrication techniques for paper analytical devices.
  • Discussion of various pretreatment, dipstick, lateral flow assay, and µPAD methodologies.
  • Exploration of established biomedical applications.

Main Results:

  • Paper diagnostic devices are significant for various applications.
  • Multiple fabrication methods exist for paper analytical devices.
  • Numerous biomedical applications have been demonstrated.

Conclusions:

  • Paper-based microfluidics hold great promise for biomedical diagnostics.
  • Further research is needed to address existing challenges and bridge research gaps.