Bibliometric analysis of microbial sulfonamide degradation: Development, hotspots and trend directions

Microbial sulfonamide degradation (MSD) is an efficient and safe treatment in both natural and engineered ecosystems. In order to systematically understand the research status and frontier trends of MSD, this study employed CiteSpace to conduct a bibliometric analysis of data from the Web of Science (WoS) and the China National Knowledge Infrastructure (CNKI) published from 2000 to 2021. During this time, China, Germany, Spain, the United States and Australia played leading roles by producing numerous high impact publications, while the Chinese Academy of Sciences was the leading research institution in this interdisciplinary research category. The Chemosphere was the top journal in terms of the number of citations. MSD research has gradually progressed from basic laboratory-based experiments to more complex environmental microbial communities and finally to deeper research on molecular mechanisms and engineering applications. Although multi-omics and synthetic community are the key techniques in the frontier research, they are also the current challenges in this field. A summary of published articles shows that Proteobacteria, Gammaproteobacteria, Burkholderiales and Alcaligenaceae are the most frequently observed MSD phylum, class, order and family, respectively, while Bacillus, Pseudomonas and Achromobacter are the top three MSD genera. To our knowledge, this study is the first to investigate the development and current challenges of MSD research, put forward future perspective, and form a relatively complete list of sulfonamide-degrading microorganisms for reference.