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Daldinans D‒G, new isoindolinone antioxidants isolated from the ascomycete Daldinia concentrica
Dae-Won Ki1, Seong-Eun Kim1, Ji-Yul Kim1,2
1Division of Biotechnology and Advanced Institute of Environment and Bioscience, College of Environmental and Bioresource Sciences, Jeonbuk National University, Gobong-ro 79, Iksan, 54596, South Korea.
Journal of Natural Medicines
|January 16, 2022
Abstract:
Four new isoindolinone derivatives, daldinans D‒G (3‒6), together with two known compounds, daldinans A and B (1 and 2), were isolated from the stroma of the ascomycete Daldinia concentrica. Chemical structures of the isolated compounds were determined by spectroscopic methods. All of these compounds exhibited antioxidant activities with IC50 values of 3.21 to 39.67 µM in the 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assay.