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Updated: Oct 6, 2025

Minimally Invasive Isolated Limb Perfusion (MI-ILP) for Locally Advanced Melanomas and Sarcomas of the Extremity
Published on: January 31, 2025
Multidisciplinary Perioperative Management of Hyperthermic-Isolated Limb Perfusion for Malignant Melanoma: A Case
Raghav Gupta1, Himanshu P Yadav1, Nishkarsh Gupta1
1Department of Onco-Anesthesia and Palliative Medicine, Dr BRAIRCH All India Institute of Medical Sciences, New Delhi, India.
Hyperthermic-isolated limb perfusion (HILP) is an established modality of treatment for patients with advanced malignant melanoma of the limb in which diseased limb is infused with high concentration of chemotherapeutic agent. There is a lack of literature addressing its perioperative implications. We present a case and discuss the need for multipronged approach, team effort, and invasive hemodynamic and metabolic monitoring.
Hyperthermic-isolated limb perfusion (HILP) is an established modality of treatment for patients with advanced malignant melanoma of the limb in which diseased limb is infused with high concentration of chemotherapeutic agent. There is a lack of literature addressing its perioperative implications. We present a case and discuss the need for multipronged approach, team effort, and invasive hemodynamic and metabolic monitoring.

