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A Defurne1, V Duquennoy-Martinot1,2, M Jeanne1

  • 1Centre de Traitements des Brûlés, Hôpital Roger Salengro, Lille, France.

Annals of Burns and Fire Disasters
|January 17, 2022
PubMed
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Recreational nitrous oxide use can cause severe frostbite injuries. This study details six cases of third-degree thigh burns from cold gas cylinders, requiring surgical intervention.

Area of Science:

  • Medical Case Reports
  • Dermatology
  • Emergency Medicine

Context:

  • Increasing recreational use of nitrous oxide (N2O).
  • N2O is inhaled from cylinders cooled by rapid gas release.
  • Cylinder contact with skin can cause cold injury.

Purpose:

  • To report cases of severe frostbite from recreational N2O use.
  • To highlight the mechanism of injury.
  • To emphasize the need for medical awareness.

Summary:

  • Six patients presented with third-degree burns on the inner thighs.
  • The burns resulted from direct contact with a rapidly cooling N2O cylinder.
  • Injuries initially appeared superficial but progressed to deep tissue damage.

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Impact:

  • Frostbite from N2O cylinders can lead to severe, full-thickness burns.
  • Surgical management, including skin grafting, may be necessary.
  • Highlights a previously underreported risk associated with recreational substance use.