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Using Whole Mount in situ Hybridization to Link Molecular and Organismal Biology
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Integrating Bioinformatics Tools Into Inquiry-Based Molecular Biology Laboratory Education Modules.

Carlos C Goller1,2, Melissa C Srougi1,3, Stefanie H Chen1,2

  • 1Biotechnology (BIT) Program, North Carolina State University, Raleigh, NC, United States.

Frontiers in Education
|January 17, 2022
PubMed
Summary

Molecular biology education now integrates online bioinformatics tools. New flexible modules (MBLEMs) blend wet-lab experiments with bioinformatics for inquiry-based learning, preparing students for diverse science careers.

Keywords:
bioinformaticscase studiesmolecular biotechnologyscience educationsoftware tools

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Area of Science:

  • Molecular Biology
  • Bioinformatics
  • Life Sciences Education

Background:

  • Online bioinformatics tools are essential in modern life sciences.
  • Molecular biology education must adapt to include bioinformatics training for career readiness.
  • Higher education needs dynamic teaching methods combining bioinformatics and lab pedagogy.

Purpose of the Study:

  • To introduce a new paradigm for molecular biology laboratory education.
  • To describe flexible, inquiry-based Molecular Biology Laboratory Education Modules (MBLEMs).
  • To highlight the integration of online bioinformatics tools into life sciences curricula.

Main Methods:

  • Development of inquiry-based Molecular Biology Laboratory Education Modules (MBLEMs) by the Biotechnology Program.
  • Incorporation of online bioinformatics tools and wet-lab experiments.
  • Alignment with national learning frameworks and evidence-based pedagogical practices.

Main Results:

  • MBLEMs offer flexible, inquiry-based exercises adaptable for various courses and institutions.
  • Students engage with current biological research areas like CRISPR and metagenomics.
  • The modules strategically combine bioinformatics with wet-lab experiments to address research questions.

Conclusions:

  • MBLEMs represent a novel approach to biology laboratory education.
  • Bioinformatics is a critical component for inquiry-based learning in life sciences.
  • These modules serve diverse learners across educational levels and disciplines.