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Published on: August 11, 2023
Esophageal motility disorders missed during endoscopy
Hirofumi Abe1, Shinwa Tanaka2, Fumiaki Kawara3
1Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe, Hyogo, 650-0017, Japan. abe627@med.kobe-u.ac.jp.
Fifteen percent of esophageal motility disorders were missed during endoscopic examination. Identifying these missed cases through clinical characteristics can improve diagnostic accuracy and patient outcomes.
Area of Science:
- Gastroenterology
- Esophageal Physiology
- Diagnostic Endoscopy
Background:
- Esophageal motility disorders are often challenging to diagnose during standard endoscopic procedures.
- Misdiagnosis can lead to delayed or incorrect treatment for patients.
Purpose of the Study:
- To determine the proportion of esophageal motility disorders that are missed during endoscopic evaluation.
- To identify the clinical characteristics associated with these missed diagnoses.
Main Methods:
- Retrospective analysis of patients diagnosed with esophagogastric junction outflow obstruction or major disorders of peristalsis via high-resolution manometry.
- Definition of missed esophageal motility disorders as any endoscopic misdiagnosis within one year prior to manometry.
- Multivariate analysis to identify predictors of missed diagnoses.
Main Results:
- 15.0% of esophageal motility disorders were missed during endoscopy within a year before manometric diagnosis.
- Independent predictors for missed diagnoses included non-dilated esophagus, epiphrenic diverticulum, transnasal endoscopy use, and combined esophagram use.
Conclusions:
- A significant proportion of esophageal motility disorders are overlooked during endoscopy.
- Understanding specific clinical features can aid endoscopists in identifying at-risk patients and improving diagnostic yield.
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