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Peripheral dentinogenic ghost cell tumour.

Ivan Cabo1, André Saura2, Ana Rita Cardoso3

  • 1Department of Stomatology, Centro Hospitalar e Universitário de Coimbra EPE, Coimbra, Portugal ivan.gon.cabo@gmail.com.

BMJ Case Reports
|January 18, 2022
PubMed
Summary
This summary is machine-generated.

Dentinogenic ghost cell tumors (DGCT) are rare neoplasms. This case report details a peripheral DGCT in a 78-year-old man, emphasizing diagnosis and treatment of this uncommon condition.

Keywords:
dentistry and oral medicineoral and maxillofacial surgerypathology

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Area of Science:

  • Oral Pathology
  • Oncology
  • Dentistry

Background:

  • Dentinogenic ghost cell tumor (DGCT) is a rare benign neoplasm characterized by aberrant keratinization, ghost cells, and dentinoid material.
  • DGCT presents in central and peripheral types with distinct clinical features.
  • Fewer than 60 cases of DGCT have been documented globally.

Observation:

  • A 78-year-old male presented with a slow-growing, painless lump in the mandible.
  • An incisional biopsy confirmed the diagnosis of peripheral dentinogenic ghost cell tumor.
  • Treatment involved radical excision and upper marginal mandibulectomy.

Findings:

  • This report documents a rare case of peripheral dentinogenic ghost cell tumor.
  • The study highlights the diagnostic process and surgical management of this rare oral neoplasm.
  • Histological examination revealed characteristic ghost cells and dentinoid material.

Implications:

  • This case contributes to the understanding of peripheral DGCT, a rare entity.
  • Accurate diagnosis and appropriate surgical intervention are crucial for managing DGCT.
  • Further research into the biological behavior of DGCT may improve patient outcomes.