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Language serves as a bridge between ideas and communication, influencing how individuals perceive and interact with the world. Psychologists have long debated whether language shapes thought or vice versa. This discussion gained grip with Edward Sapir and Benjamin Lee Whorf in the 1940s, who proposed that language determines thought, a concept known as linguistic determinism. They suggested that the vocabulary and structure of a language influence how its speakers think and perceive reality.
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Systematic Hearing Performance Evaluation Process for Adolescents with Cochlear Implantation at Early Ages
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Audiological profile and cochlear functionality in Williams syndrome.

Liliane Aparecida Fagundes Silva1, Rachel Sayuri Honjo Kawahira2, Chong Ae Kim2

  • 1Departamento de Fisioterapia, Fonoaudiologia e Terapia Ocupacional, Faculdade de Medicina - FM, Universidade de São Paulo - USP - São Paulo (SP), Brasil.

Codas
|January 19, 2022
PubMed
Summary
This summary is machine-generated.

Williams syndrome (WS) individuals often experience hearing loss and cochlear dysfunction, particularly affecting high frequencies. Transient Evoked Otoacoustic Emissions (TEOAE) testing is crucial for audiological evaluations in this population.

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Area of Science:

  • Audiology
  • Genetics
  • Neuroscience

Background:

  • Williams syndrome (WS) is a genetic disorder associated with various health issues, including potential auditory pathway abnormalities.
  • Previous research suggests a higher prevalence of hearing problems in individuals with WS.

Purpose of the Study:

  • To comprehensively evaluate cochlear functionality in individuals diagnosed with Williams syndrome.
  • To identify specific audiological profiles and potential hearing impairments in WS patients.

Main Methods:

  • A cohort of 39 participants (22 with WS, 17 controls) aged 7-17 years underwent audiological assessments.
  • Evaluations included pure tone audiometry, acoustic immittance measurements, and Transient Evoked Otoacoustic Emissions (TEOAE).
  • Audiological data from WS individuals were analyzed and compared to those with typical development.

Main Results:

  • Fifty percent of individuals with WS exhibited hearing loss, predominantly sensorineural (78.95%) and mild to moderate in severity.
  • Hearing impairment primarily affected higher frequencies (above 3 kHz).
  • A higher incidence of absent or reduced amplitude TEOAE responses was observed in the WS group.

Conclusions:

  • Williams syndrome is associated with cochlear hair cell dysfunction, particularly in the basal region.
  • Transient Evoked Otoacoustic Emissions (TEOAE) serve as a valuable tool for routine audiological screening in WS individuals.
  • Early identification of cochlear dysfunction through TEOAE can inform audiological management strategies.