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A microcomputer program for the generation of random grid squares in quantitative analysis
1Wadsworth Center for Laboratories and Research, New York State Department of Health, Albany 12201.
Journal of Electron Microscopy Technique
|November 1, 1987
Summary
Minimize subjectivity in quantitative analysis using finder grids and a computer program. This method enhances accuracy for asbestos and microparticle detection in environmental samples.
Area of Science:
- Environmental Science
- Analytical Chemistry
- Microscopy
Background:
- Subjectivity in selecting random grid squares can compromise the accuracy of routine quantitative analysis.
- Accurate microparticle quantification is crucial for environmental monitoring and quality control.
Purpose of the Study:
- To present a method for circumventing subjectivity in random grid square selection for quantitative analysis.
- To introduce a simple BASIC computer program for generating random grid-square numbers for sequential analysis.
Main Methods:
- Utilizing finder grids in conjunction with a computer program to select random grid squares.
- Developing a BASIC program to generate a list of random grid-square numbers for analysis.
- Applying the method to the quantitation of asbestos and other microparticles in environmental samples.
Main Results:
- The combined use of finder grids and the computer program effectively eliminates subjectivity in grid square selection.
- The method was successfully applied to quantify asbestos and microparticles in environmental samples, demonstrating its practical utility.
Conclusions:
- The described method offers an objective approach to quantitative analysis, improving reliability.
- This technique is valuable for quality control, cross-referencing analyses, and the study of biological specimens.