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Updated: Oct 6, 2025

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Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
Published on: May 17, 2024
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Progress in breast cancer surgical management
Francesca Magnoni1, Giovanni Corso1,2
1Division of Breast Surgery, IEO European Institute of Oncology, IRCCS.
Summary
Breast cancer surgery has advanced significantly, improving patient outcomes and quality of life. Research focuses on personalized, less invasive surgical techniques and multimodal treatment strategies.
Area of Science:
- Oncology
- Surgical Oncology
- Genomics
Background:
- Breast cancer surgical practices have evolved over 40 years.
- Scientific advancements aim to balance oncological radicality with improved quality of life and aesthetics.
- Key developments include imaging, molecular profiling, and genomic characterization.
Purpose of the Study:
- To review the evolution of breast cancer surgery.
- To highlight advancements in surgical techniques and personalized treatment.
- To emphasize the trend towards less invasive approaches and precision surgery.
Main Methods:
- Review of scientific literature and clinical practice changes over four decades.
- Analysis of progress in imaging, molecular signature characterization, and genomic profiling.
- Examination of trends in primary breast surgery and axillary staging.
Main Results:
- Significant improvements in breast cancer surgery impacting clinical practice.
- Progress in personalized prevention and treatment through advanced diagnostics.
- A clear trend towards limited surgical approaches and enhanced technical precision.
Conclusions:
- Multimodal management and individualized treatment are central to current breast cancer research.
- Continued research aims to refine personalized breast cancer prevention and treatment strategies.
- The future of breast cancer surgery emphasizes precision and tailored patient care.
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