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Risk factors for hypertension and diabetes comorbidity in a Korean population: A cross-sectional study

Jeong Hee Chi1, Bum Ju Lee2

  • 1Department of Computer Science and Engineering, Konkuk University, Seoul, Republic of Korea.

Plos One
|January 19, 2022
PubMed

Insights

Hypertension and diabetes comorbidity (HDC) in older adults is linked to body composition. Fat and lean mass showed stronger associations with HDC than diabetes or hypertension alone, especially in women.

Area of Science:

  • Gerontology
  • Cardiovascular Health
  • Metabolic Disorders

Background:

  • Hypertension and diabetes are significant risk factors for cardiovascular disease and common comorbidities.
  • No prior studies have investigated the link between anthropometry, bone mineral density, body composition in specific regions, and hypertension and diabetes comorbidity (HDC).

Purpose of the Study:

  • To explore the association between hypertension and diabetes comorbidity (HDC) and various risk factors related to specific body regions in older Korean adults.
  • To identify regional body composition differences associated with HDC.

Main Methods:

  • A cross-sectional study involving 7,978 Korean adults aged 50 years and older.
  • Binary logistic regression analysis was used to examine associations between normal groups and diabetes, hypertension, and HDC groups.
  • Complex sample data analysis was employed.

Main Results:

  • HDC prevalence was 11.27% in men and 10.05% in women.
  • In men, waist-to-height ratio was significantly associated with HDC, while leg fat mass showed negative associations with diabetes, and leg lean mass and trunk fat mass were associated with hypertension.
  • In women, leg fat mass was strongly negatively associated with HDC, and waist circumference and waist-to-height ratio were significantly associated with hypertension and diabetes.

Conclusions:

  • HDC demonstrated a stronger association with regional fat and lean mass compared to isolated diabetes or hypertension.
  • The relationship between HDC and body fat variables was more pronounced in women than in men.
Abstract

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