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LAMN as a differential diagnosis for abdominal pain: a case report from Syria

Joudi Tarabishi1, Alma Douedari1, Tahreer Almasalmeh2

  • 1Faculty of Medicine, University of Aleppo, Aleppo, Syria.

Journal of Surgical Case Reports
|January 20, 2022
PubMed

Insights

Low-grade appendiceal mucinous neoplasms (LAMNs) are rare tumors that can mimic other conditions. This case highlights the importance of pathological examination for accurate LAMN diagnosis.

Area of Science:

  • Gastroenterology
  • Pathology
  • Oncology

Background:

  • Low-grade appendiceal mucinous neoplasms (LAMNs) are uncommon appendiceal tumors, representing less than 0.3% of appendectomy specimens.
  • LAMNs are the primary cause of pseudomyxoma peritonei, a condition characterized by mucinous ascites.
  • These neoplasms can present with vague symptoms, leading to potential misdiagnosis as acute appendicitis or other abdominal masses.

Observation:

  • A 77-year-old patient presented with a 15-day history of abdominal pain, chills, and hyperthermia.
  • Initial imaging via ultrasound and computed tomography suggested the need for surgical intervention.
  • A right hemicolectomy was performed based on the imaging findings.

Findings:

  • Pathological examination of the surgical specimen confirmed the diagnosis of LAMN.
  • Microscopic study is crucial for differentiating LAMN from mucinous adenocarcinomas.
  • Macroscopic appearance of the appendix in LAMN can range from normal to dilated.

Implications:

  • Accurate diagnosis of LAMN is essential to prevent misdiagnosis and ensure appropriate management.
  • This case underscores the role of surgical pathology in identifying rare appendiceal neoplasms.
  • Understanding the clinical presentation and diagnostic challenges of LAMN is vital for patient care.

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