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Updated: Oct 6, 2025

Microscopic Replantation of Penile Glans Amputation Due to Circumcision
Published on: June 3, 2022
Penile calciphylaxis-a complicated case managed with circumcision and glansectomy.
Ellen O'Beirn1, Muheilan Muheilan1, Rowan Casey1
1Department of Urology, Tallaght University Hospital, Dublin D24NR0A, Ireland.
Penile calciphylaxis, a rare condition in end-stage renal failure (ESRF) patients, involves small vessel calcification causing skin ischemia. Surgical intervention, including glansectomy, successfully treated a severe case, avoiding partial penectomy.
Area of Science:
- Nephrology
- Vascular Medicine
- Dermatology
Background:
- Penile calciphylaxis is a rare and severe manifestation of calcifying uremic arteriolopathy.
- It primarily affects patients with end-stage renal failure (ESRF).
- The condition involves calcification of small penile vessels, leading to ischemic skin changes and significant pain.
Observation:
- A case of penile calciphylaxis in an ESRF patient presented with a necrotic glans penis and persistent pain.
- Initial conservative management proved insufficient.
- The patient underwent surgical intervention, including circumcision and glansectomy.
Findings:
- Surgical management, specifically glansectomy, was effective in treating the necrotic penile tissue and resolving pain.
- The patient avoided a more extensive procedure, such as a partial penectomy.
- Complete recovery was achieved following the surgical intervention.
Implications:
- This case highlights the potential benefit of surgical intervention in managing complex penile calciphylaxis.
- Aggressive management may prevent the need for partial penectomy in select cases.
- Further research into optimal treatment strategies for penile calciphylaxis is warranted.
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